Potassium Dry Syrup [Amoxicillin-Clavulanate Potassium (7:1)]

Adult dose

For recurrent tonsillitis and infections of mild to moderate severity in the upper respiratory tract, lower respiratory tract, urinary tract, and skin/soft tissue infections, take 25 mg/3.6 mg per kg body weight divided into two doses per day. For moderate infections such as otitis media, sinusitis in the upper respiratory tract, bronchopneumonia in the lower respiratory tract, and severe urinary tract infections, take 45 mg/6.4 mg per kg body weight divided into two doses per day. To minimize potential gastrointestinal intolerance.

Child dose

The 7:1 syrup is not suitable for children under 2 months of age. Pediatric patients with renal impairment should not use the 7:1 syrup. For recurrent tonsillitis, upper respiratory infections, lower respiratory infections, urinary tract infections, and skin/soft tissue infections of mild to moderate severity.

This drug is a beta-lactam antibiotic and should not be used in patients with a hypersensitivity to penicillins or cephalosporins. Special caution is necessary for patients with infectious mononucleosis or lymphocytic leukemia due to the higher risk of rashes. It should be avoided in patients with a history of liver dysfunction or jaundice due to the risk of recurrence. Additionally, patients with lactose intolerance or certain genetic metabolic disorders should not use this drug due to the lactose content. Patients with impaired liver function or severe renal impairment may have increased drug concentrations, thus dosing intervals should be adjusted or used carefully. Patients with allergic diathesis or those who easily develop bronchial asthma, skin rashes, etc., should also be cautious. Patients with difficulty in oral intake, the elderly, or those in poor general condition may exhibit symptoms of vitamin K deficiency, which needs to be monitored. In cases of gastrointestinal diseases presenting with vomiting or diarrhea, drug absorption may not occur properly. Taking this medication may cause gastrointestinal adverse reactions including diarrhea, gastrointestinal discomfort, vomiting, loss of appetite, and abdominal pain. If severe diarrhea or abdominal pain occurs, treatment should be immediately discontinued, and medical attention should be sought. Rarely, liver abnormalities like elevated liver enzymes or cholestatic jaundice may occur, so liver function tests should be conducted during long-term therapy. Serious skin reactions such as skin rashes, itching, or in severe cases, Stevens-Johnson syndrome have also been reported; these symptoms require immediate discontinuation of the medication. Changes in blood tests such as leukopenia or thrombocytopenia can also occur rarely, and thus, patients should be carefully monitored for signs of bleeding. Central nervous system side effects such as anxiety, confusion, or seizures can arise, and immediate reporting of such symptoms is essential. Kidney function abnormalities may occur, requiring kidney function tests as well. This medication can interact with other drugs; thus, patients taking anticoagulants, other antibiotics, anti-inflammatory drugs, or immunosuppressants should inform their healthcare provider. Pregnant women or those who may become pregnant should particularly avoid use during the first three months, and nursing mothers should also exercise caution due to potential adverse reactions in the baby. The safety of this medication for children, especially newborns or premature infants under 2 months of age, has not been established, so caution is advised. Elderly patients may exhibit more adverse reactions due to diminished body function, so dosage and intervals should be adjusted and monitored closely. This medication should be shaken well before use, stored in a sealed container to keep it away from air or moisture, and refrigerated post-preparation, using within 7 days. In case of overdose, symptoms like gastrointestinal distress, renal failure, seizures, or severe allergic reactions may occur; immediate medical attention is necessary. Long-term use of this medication may lead to antibiotic resistance, so it is important to take it only for the minimum necessary duration. Additionally, if diarrhea worsens during or after antibiotic use, the possibility of pseudomembranous colitis should prompt rapid contact with healthcare professionals.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blistering, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress associated with coughing and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination problems

Mild side effects

• Diarrhea
• pseudomembranous colitis
• dyspepsia
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This drug must be stored in a tightly sealed container to prevent exposure to air or moisture. It should be kept in a cool place between 1 and 25 degrees Celsius.

Appearance

A white powder with a unique smell that dissolves when used as a syrup.

Package unit

50 milliliters/bottle