Medication info

Pactoral Tablet

Prescription medicationApproval withdrawn
Ingredient · strength
Sulfamethoxazole›Strength being verifiedTrimethoprim›Strength being verified
Manufacturer / importer
(주)에이프로젠바이오로직스
Appearance
White round tablet
Packaging
30, 50, 100, 150, 200, 240, 300, 400, 500, 1000 tablets
Approval status
Approval withdrawn

MFDS item code 199600329 · Notified 1996.12.18

This product's status changed to Approval withdrawn on 2023.03.14. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of respiratory infections such as acute and chronic bronchitis, pneumonia
Who uses it
Adults · Children
Adult dosage
Adults and children aged 12 years and older: Administer 2 tablets at a time, 2 times a day every 12 hours orally after meals. For long-term treatment (more than 14 days), use a maintenance dose of 1 tablet at a time, 2 times a day, and for severe infections, a maximum dose of 3 tablets at a time.
Children's dosage
Children under 11 years of age: Administer 6mg of trimethoprim and 30mg of sulfamethoxazole per kg of body weight orally divided into two doses per day. Ages 6-11: 1 tablet at a time, 2 times a day Ages 3-5: 1/2 tablet at a time, 2 times a day

Ingredients

Manufacturer
(주)에이프로젠바이오로직스

Efficacy & effects

Treatment of respiratory infections such as acute and chronic bronchitis, pneumonia

  • Acute and chronic bronchitis
  • bronchiectasis
  • pneumonia
  • sinusitis
  • acute and chronic cystitis
  • pyelonephritis
  • urethritis
  • prostatitis
  • gonorrhea
  • otitis media
  • gastroenteritis
  • typhoid fever
View approved original text

This medication is effective against various bacteria such as Escherichia coli, Streptococcus pneumoniae, and Neisseria gonorrhoeae. It is used for respiratory infections such as acute and chronic bronchitis, pneumonia, and sinusitis, and is effective for urinary tract infections such as cystitis, pyelonephritis, and urethritis. It is also applicable for bacterial infections such as gonorrhea, gastroenteritis, and typhoid fever. It is used for skin and soft tissue infections like wound infections and impetigo, helping with the treatment of infections. It is widely used to treat bacterial infections in various parts of the body.

Dosage and Administration

Adult dosage

Adults and children aged 12 years and older: Administer 2 tablets at a time, 2 times a day every 12 hours orally after meals. For long-term treatment (more than 14 days), use a maintenance dose of 1 tablet at a time, 2 times a day, and for severe infections, a maximum dose of 3 tablets at a time.

Children's dosage

Children under 11 years of age: Administer 6mg of trimethoprim and 30mg of sulfamethoxazole per kg of body weight orally divided into two doses per day. Ages 6-11: 1 tablet at a time, 2 times a day Ages 3-5: 1/2 tablet at a time, 2 times a day

Precautions

This medication may cause serious skin adverse reactions and blood disorders, as well as significant side effects such as liver and kidney dysfunction; therefore, if symptoms arise during use, administration must be discontinued immediately. This drug is not suitable for treating certain infections, and individuals with sulfamethoxazole allergies, pregnant women, neonates, preterm infants, and patients with certain enzyme deficiencies should not use it. Patients with blood disorders or weakened liver and kidney function, the elderly, and those with allergic predispositions should exercise extra caution when using this medication. Regular testing such as blood tests and liver and kidney function tests should be conducted during administration to detect and manage side effects early. This medication can interact with several drugs, so if taking other medications, consult with healthcare professionals, especially when combined with anticoagulants, anticonvulsants, and immunosuppressants. It is safest for women who are pregnant or may become pregnant and nursing mothers not to use this drug. If it must be used, breastfeeding should be discontinued. In case of overdose, symptoms may include vomiting, diarrhea, headache, dizziness, and in severe cases, blood disorders or kidney damage may occur; therefore, immediate medical attention is necessary. Even with long-term administration, there is a potential for side effects, so dosage and duration must be strictly followed according to medical guidance.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blistering, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Sore throat
  • fever
  • joint pain
  • cough
  • shortness of breath
  • purpura
  • itching
  • erythema multiforme
  • blisters
  • rash
Show 27 more
  • Henoch-Schönlein purpura
  • photosensitivity
  • elevated AST
  • ALT
  • and ALP
  • hepatitis
  • bloody stools
  • gastrointestinal disorders
  • loss of appetite
  • nausea
  • vomiting
  • diarrhea
  • abdominal discomfort
  • glossitis
  • constipation
  • cheilitis
  • stomatitis
  • cholestasis
  • membranous enterocolitis
  • acute pancreatitis
  • arthralgia
  • myalgia
  • palpitations
  • flushing
  • tinnitus
  • hypokalemia
  • low

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a light-resistant container. It should also be kept in a sealed container to prevent air from entering and stored at room temperature, which is most suitable. Proper storage helps maintain the drug's effectiveness and safety over time.

Appearance and packaging

Appearance

White round tablet

Package unit

30, 50, 100, 150, 200, 240, 300, 400, 500, 1000 tablets

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.