Daehan Aminophylline Injection (2.5%)

Key information summary

Efficacy & effects

This medication is used to relieve various symptoms caused by obstructive airway disorders such as bronchial asthma, asthmatic bronchitis, emphysema, and chronic bronchitis. It also helps prevent attacks of cardiac asthma and improve Cheyne-Stokes breathing. In summary, this drug is effective in alleviating symptoms related to respiratory diseases and cardiac function abnormalities.

Dosage

Adults: For aminophylline anhydrous, dilute 250 mg once in 1 to 2 times daily with normal saline or dextrose injection and administer intravenously or via drip slowly over 5 to 10 minutes. The dosing interval should be more than 8 hours, and the maximum dose is 12 mg per kg of body weight per day. Adjust as appropriate based on symptoms.

Precautions

The drug's concentration must be regularly tested to adjust the dosage appropriately. If the blood concentration is too high, serious side effects such as seizures or cardiac rhythm abnormalities may occur. Patients with heart diseases should be particularly cautious when using this drug. When using glass ampoule injections, care must be taken to avoid glass fragments, and special attention is needed when administering to children or the elderly. Patients who are allergic to this drug or its components, or who have previously experienced serious side effects, should not use it. Patients with specific conditions such as gastric or duodenal ulcers, porphyria, acute tachyarrhythmia, and myocardial infarction should also avoid using this drug for safety. In certain patient groups such as those with epilepsy, hyperthyroidism, renal or hepatic dysfunction, hypertension, the elderly, pregnant women, and nursing mothers, it should be used with caution and under medical guidance. This drug may cause various side effects such as headaches, insomnia, dizziness, palpitations, nausea, skin rashes, and if any unusual symptoms occur, healthcare providers should be notified immediately. Interactions may occur when using this drug with other medications, so all medications being taken should be disclosed to healthcare providers for careful monitoring. Women who are pregnant or breastfeeding should consult a doctor before using this drug, considering its potential effects on the fetus or infant. It is advisable not to administer to infants under 6 months of age, and dosage adjustment and condition monitoring are necessary for children and the elderly. Rapid intravenous injection of this drug may increase the risk of side effects, so it should be diluted and administered slowly. In case of overdose, severe symptoms such as vomiting, seizures, and cardiac abnormalities may arise, requiring immediate emergency treatment and proper management of blood concentration. Since managing blood concentration is very important for this drug, regular tests are necessary, and healthcare providers should be consulted immediately if adverse reactions occur.

Side effects

Seizures, supraventricular tachycardia, shock, paralysis, coma, severe headache

Alternatives / Same-ingredient medications

• 

  Daewon Aminophylline Tablet (Aminophylline Hydrate)

  Same ingredient
• Jeil Aminophylline Injection

  Same ingredient
• 

  Ascontin Sustained Release Tablets (Aminophylline Hydrate)

  Same ingredient
• 

  Ascontin Sustained Release Tablets (Aminophylline Hydrate)

  Same ingredient

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