Ascontin Sustained Release Tablets (Aminophylline Hydrate)

Adult dose

(Extended-release tablet) 225 mg Adults: The initial dose is 225 mg of aminophylline hydrate twice daily (morning and evening) by oral administration. Depending on symptoms, the dose may be increased to 450 mg per dose twice daily (morning and evening). Do not chew or crush the tablets. Adjust the dose as appropriate according to symptoms.

Child dose

(Extended-release tablet) 100 mg Children: Administer the following doses of aminophylline hydrate orally. Do not chew or crush the tablets. 8 ∼ 12 years: 100 ∼ 200 mg per dose twice daily (morning and evening) 4 ∼ 7 years: 100 mg per dose twice daily (morning and evening) Adjust the dose as appropriate according to age and symptoms.

The blood concentration of this medication should be monitored periodically to adjust dosages. If blood concentration is too high, severe side effects such as convulsions or arrhythmias may occur. Patients with heart disease should take special precautions when using this medication. When using the injectable form in ampoules, handle it carefully to avoid glass particles contamination, and more caution is required for children and the elderly. This medication or its ingredients, or similar class medications should not be used if there is an allergy or history of severe side effects, or if there are gastrointestinal ulcers or specific blood disorders. Additionally, patients with acute arrhythmias or myocardial infarction should avoid using the injectables. Patients with epilepsy, thyroid dysfunction, kidney or liver impairment, children, the elderly, or pregnant or breastfeeding women should use this medication with caution, and those with chronic alcoholism, heart failure, or diabetes should also be careful. This medication can cause various side effects such as headache, insomnia, anxiety, dizziness, nausea, vomiting, arrhythmia, and skin rash. Rarely, muscle damage or liver function abnormalities may occur, so any symptoms should be reported to a healthcare professional immediately. When used with other medications, interactions may occur, thus dosage adjustment and monitoring are essential, especially when used with central nervous system stimulants, certain antibiotics, heart medications, or anticonvulsants. Smoking or drinking can also affect the effectiveness of this medication, so caution is advised. Pregnant or breastfeeding women should consult a doctor before use, as it may affect the fetus or infant. It is advisable not to use this medication in infants under 6 months, and caution should be taken when used in children with a history of convulsions. In the elderly, dosage adjustments may be necessary due to possible increased drug concentration from hepatic impairment. This medication is safer when administered slowly while monitoring blood concentration, as rapid injection increases the risk of side effects. In case of overdose, serious symptoms such as vomiting, convulsions, and heart abnormalities may occur, requiring immediate emergency care and potential treatment to lower blood concentration.

• Cramps
• supraventricular tachycardia
• shock
• headache
• insomnia
• central nervous system excitation
• anxiety
• dizziness
• tinnitus
• tremor

This medication is sensitive to light and should be stored in a tightly closed container that is protected from light. It is important to maintain the storage temperature between 1 and 30 degrees Celsius.

Appearance

Round-shaped tablet with a very light yellow color

Package unit

300 tablets/bottle