Pregabalin Oral Dispersible Tablet 75 mg (Pregabalin)

Adult dose

This medication, pregabalin, is administered orally, divided into two doses per day regardless of meals, placing it on the tongue to disperse and swallow without water. 1. Neuropathic Pain - Peripheral neuropathic pain: Starting dose of 150 mg per day; may increase to 300 mg per day after 3-7 days and can be further increased to a maximum of 600 mg at 7-day intervals if needed. - Central neuropathic pain: Starting

Child dose

Safety and efficacy data for children under 12 years and adolescents aged 12-17 years are insufficient; therefore, administration is not recommended.

This medication may pose a risk of causing mental health issues such as suicidal thoughts or behaviors; therefore, if any changes in mood or behavior occur during treatment, it is essential to inform healthcare professionals immediately. Patients with allergies to this medication or those who have previously shown hypersensitivity to any ingredients should not take it. Diabetic patients may experience weight gain while taking this medication, and may need to adjust their diabetes medications accordingly. If symptoms of angioedema such as facial or oral swelling develop, the medication should be discontinued immediately. Elderly patients should exercise caution while taking this medication as dizziness or drowsiness may increase the risk of falls and injuries; particular care should be taken when first starting treatment. Blurred vision or changes in eyesight may occur; if these symptoms appear, consultation with a healthcare professional is advised. When switching from another antiepileptic drug to this medication solely, as there is a lack of sufficient data, it should be done under professional guidance. Abrupt discontinuation of this medication may cause withdrawal symptoms such as insomnia, headache, anxiety, depression, or seizures; therefore, it should be tapered gradually according to healthcare professionals’ instructions. Patients with a history of substance abuse may be at increased risk of dependency on this medication and should take precautions. Dosing adjustments may be necessary for patients with impaired renal function. Patients with severe cardiac disease should use this medication cautiously as it may exacerbate heart issues such as congestive heart failure. Concurrent use with opioids may enhance central nervous system depressant effects; therefore, caution is warranted. Patients with compromised respiratory function or the elderly may have a significant risk of severe respiratory depression and should only use the medication after consulting with a healthcare professional. In early pregnancy, there may be a risk of congenital malformations to the fetus, so women who are pregnant or planning to become pregnant must consult with a healthcare professional and use effective contraception. Lactating women should be aware that this medication can pass into breast milk and may affect the infant, hence breastfeeding should be avoided or a discussion with healthcare providers is necessary during treatment. When engaging in hazardous activities such as driving or operating machinery, care should be taken due to the risk of accidents from dizziness or drowsiness. If severe skin rashes, blisters, or red spots occur while taking this medication, it should be discontinued immediately and healthcare professionals should be informed. In cases of overdose, symptoms such as drowsiness, confusion, depression, and seizures may occur, necessitating immediate emergency treatment. Keep out of reach of children and avoid transferring to other containers, as this could affect the quality of the medication.

Serious side effects

Hives, severe swelling, angioedema, facial swelling, swelling of the mouth, throat, and upper airways, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth or eyes, severe skin reactions, shortness of breath, asthma attacks, cough with fever accompanied respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and alarming

Mild side effects

• Dizziness
• drowsiness
• increased appetite
• loss of appetite
• hypoglycemia
• confusion
• spatial disorientation
• irritability
• depression
• euphoric feelings

This medication should be stored in a tightly closed container to protect it from exposure to air and moisture. It’s advisable to maintain a storage temperature between 1 degrees and 30 degrees Celsius.

Appearance

Light orange rhomboid oral dispersible tablet

Package unit

30 tablets/PTP [(10 tablets/PTP × 3)], 100 tablets/PTP [(10 tablets/PTP × 10)]