Medication info

Allpain Injection Solution (Vial) (Nepofen Hydrochloride)

Prescription medicationInjectionsIntravenous injection
Ingredient · strength
Nefopam Hydrochloride›10mg / 1mL
Manufacturer / importer
Korea Pharmbio Co., Ltd.
Appearance
A colorless and transparent liquid contained in a colorless and transparent vial.
Packaging
10 vials/box [(2mL/vial × 10)]
Approval status
Active

MFDS item code 202503265 · Approved 2025.12.12

Summary

Main use
Relief of acute pain (such as postoperative pain)
Who receives it
Adults
Adult administration
Administer 20 mg of nefopam hydrochloride per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer intravenous injections slowly over at least 15 minutes. After administration, it is preferable to have the patient lie still and rest for 15-20 minutes. When added to an infusion solution such as electrolytes or glucose, administer 30 mg over 4 hours or 40 mg over 6-8 hours, in proportion to the infusion time. It is recommended to avoid mixing this medicine with other medicines for injection. Adjust the dose appropriately according to age and symptoms.

Ingredients

Manufacturer
Korea Pharmbio Co., Ltd.

Efficacy & effects

Relief of acute pain (such as postoperative pain)

  • Acute pain
  • postoperative pain
View approved original text

This medication is used to relieve acute pain. It is particularly helpful in reducing pain that occurs after surgery, aiding patients in their rapid recovery. It effectively alleviates pain to support minimal discomfort in daily life. It is used for relief of acute pain and postoperative pain.

How it is given

Adult administration

Administer 20 mg of nefopam hydrochloride per dose by intramuscular or intravenous injection. If necessary, repeat every 6 hours, not exceeding 120 mg per day. Administer intravenous injections slowly over at least 15 minutes. After administration, it is preferable to have the patient lie still and rest for 15-20 minutes. When added to an infusion solution such as electrolytes or glucose, administer 30 mg over 4 hours or 40 mg over 6-8 hours, in proportion to the infusion time. It is recommended to avoid mixing this medicine with other medicines for injection. Adjust the dose appropriately according to age and symptoms.

Precautions

This medication should not be used in patients with epilepsy or myocardial infarction. It should also not be administered to patients taking MAO inhibitors, individuals allergic to this medication or its ingredients, children under 15 years old, patients with a history of seizures, patients with urinary retention due to urethral or prostate issues, and patients with closed-angle glaucoma. Caution is advised when using this medication in elderly patients, pregnant women, and breastfeeding women, as well as in patients taking anticholinergic medications. This medication can cause decreased appetite, nausea, drowsiness, vomiting, excessive sweating, dizziness, increased heart rate, dry mouth, urinary retention, injection site pain, headache, blurred vision, fatigue, nervousness, sleep disturbances, insomnia, agitation, and allergic reactions. These side effects vary with the drug dosage and typically resolve with repeated dosing. When treating inflammation or pain, it is crucial to address the underlying cause, and this medication assists in alleviating symptoms. Use should consider the degree of acute inflammation and pain, and prolonged use of the same medication should be avoided. When used for infectious inflammation, it should be administered with antibiotics or antifungals under careful observation. In elderly patients, the minimal effective dosage should be used with heightened awareness of potential side effects. Patients with impaired liver and kidney function may be affected in the metabolism and excretion of this medication, thus caution is necessary. This medication may cause drowsiness or decreased alertness, so it is advisable not to use it when engaging in activities that require attention, such as driving or operating machinery. The safety of this medication in combination with narcotic analgesics has not yet been established, and when used with acetaminophen-containing drugs, careful monitoring for liver toxicity risk is advised. The use of this medication in conjunction with other non-steroidal anti-inflammatory drugs is not recommended. Caution should be exercised when co-administering with sympathomimetic agents or anticholinergic medications, as side effects may be increased. Use of this medication is not recommended for pregnant or breastfeeding women, and it is not used in children due to the establishment of safety and efficacy not being confirmed. This medication is not recommended for elderly patients due to anticholinergic side effects. In case of overdose, immediate consultation with a physician or pharmacist is required, and monitoring of heart and respiratory status may be necessary. It is advisable to avoid mixing this medication with other drugs for injection. When storing, keep in a sealed container away from children's reach, avoiding direct sunlight, and storing in a cool, dry place.

Side effects

  • loss of appetite
  • gastrointestinal disorder
  • nausea
  • drowsiness
  • vomiting
  • hyperhidrosis
  • dizziness
  • tachycardia
  • palpitations
  • thirst
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  • urinary retention
  • sweating
  • pain at the injection site
  • headache
  • blurred vision
  • fatigue
  • irritability
  • sleep disturbances
  • insomnia
  • agitation
  • hypersensitivity
  • hallucinations
  • abuse
  • drug dependence
  • convulsions
  • urticaria
  • angioedema
  • anaphylactic shock
  • pink urine
  • pallor

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent exposure to air, preferably at room temperature between 1 and 30 degrees. Proper storage will maintain the medication's effectiveness and ensure safe usage.

Appearance and packaging

Appearance

A colorless and transparent liquid contained in a colorless and transparent vial.

Package unit

10 vials/box [(2mL/vial × 10)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.