Briveta 50 mg Tablet (Brivaracetam)

Adult dose

Take this medicine twice daily. The recommended initial dose is 25mg or 50mg per dose, based on the healthcare provider’s assessment of the potential side effects in relation to seizure reduction. Based on clinical response and tolerability, the dose may be increased or decreased from 50mg per day[25mg twice daily] to 200mg per day[100mg twice daily]. This medicine is a film-coated tablet. Swallow it whole with water. It may be taken with or without food. If you miss a dose If you miss one or more doses, take one dose as soon as you remember, and then take the next dose at the next morning or evening dose time. When discontinuing treatment If you wish to stop taking this medicine, gradually reduce the dose by 50mg per day at 1-week intervals. After taking 50mg per day for 1 week, a dose of 20mg per day is recommended for the final week (see section ‘1. Warnings’). Elderly patients (65 years and older) Dose adjustment is not required for elderly patients. Clinical experience in elderly patients aged 65 years and older is limited. Renal impairment Dose adjustment is not required in patients with renal impairment. This medicine is not recommended for patients with end-stage renal disease who are receiving hemodialysis. Hepatic impairment Exposure to this medicine is increased in patients with hepatic impairment. The recommended initial dose for patients with hepatic impairment is 50mg per day[25mg twice daily], and the recommended maximum dose is 150mg per day[75mg twice daily].

As this medication is an anticonvulsant, there may be suicidal thoughts or behavior during treatment, so patients and their caregivers should carefully monitor for these symptoms. It may cause side effects like drowsiness, fatigue, dizziness, and coordination disorders affecting the central nervous system, which can occur particularly during the early stages of treatment or at any time during treatment. Suddenly stopping the medication can increase the frequency of seizures, so the dosage must be reduced gradually as per the doctor's instructions. Patients with hypersensitivity to this drug or certain genetic conditions such as lactose intolerance should avoid taking it. Patients with impaired liver function may need dose adjustment, so consultation with a physician is necessary. Mental changes like depression, anxiety, or suicidal thoughts may occur during treatment with this medication, and if severe rashes or blisters appear on the skin, a doctor should be notified immediately. Avoid alcohol as it may further impair mental and motor functions. Interactions may occur with other anticonvulsant medications or certain drugs, so notify your physician of any other medications currently being taken. It should be taken during pregnancy only if the benefits outweigh the risks, as safety for the fetus has not been established. Nursing mothers should also consult a doctor before use. Safety and efficacy have not yet been confirmed in children under 16, so caution is advised. This medication may cause drowsiness or dizziness, so caution is required while driving or operating machinery. In case of overdose, symptoms such as drowsiness, dizziness, anxiety, and insomnia may appear, and as there is no specific antidote, immediate medical attention is required. Finally, keep the medication out of the reach of children and do not transfer it to another container to maintain safety and quality.

suicidal ideation

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is advisable to maintain the storage temperature between 1°C and 30°C at room temperature. This will help ensure the medication's effectiveness and safety over time.

Appearance

Yellow, egg-shaped film-coated tablet

Package unit

PTP - 30 tablets/box [(10 tablets/PTP * 3)]