Bukwang Brivaracetam Tablets 10 mg (Brivaracetam)

Adult dose

This medicine is taken twice daily. The recommended initial dose is 25mg or 50mg per dose, based on the healthcare professional's assessment of potential adverse effects relative to seizure reduction. Based on clinical response and tolerability, the dose may be increased or decreased from 50mg per day [25mg per dose, twice daily] to 200mg per day [100mg per dose, twice daily]. Swallow this film-coated tablet whole with water. It may be taken with or without food. If you miss a dose If you miss one or more doses, take one dose as soon as you remember, and then take the next dose at the next scheduled morning or evening time. Discontinuation If you wish to stop taking this medicine, gradually reduce the dose by 50mg per day at 1-week intervals. After taking 50mg per day for 1 week, a dose of 20mg per day is recommended for the final week (see section 2. Warnings). Older adults (65 years and older) No dosage adjustment is required in older adults. Clinical experience in patients aged 65 years or older is limited. Renal impairment No dosage adjustment is required in patients with renal impairment. This medicine is not recommended for patients with end-stage renal impairment who are receiving hemodialysis. Hepatic impairment Exposure to this medicine is increased in patients with hepatic impairment. The recommended initial dose for patients with hepatic impairment is 50mg per day [25mg per dose, twice daily], and the recommended maximum dose is 150mg per day [75mg per dose, twice daily].

This medication is used to treat epilepsy and can cause serious mental health issues like suicidal thoughts or behaviors; thus, patients and guardians should carefully monitor for these symptoms. Central nervous system-related side effects such as drowsiness, fatigue, dizziness, and motor control disturbances may occur at the beginning of treatment or at any time during therapy, so caution is advised. Sudden discontinuation of this medication may increase the risk of worsening seizures, so dosage should be gradually reduced according to a physician’s instructions. Patients with allergic reactions to this medication or with a genetic inability to digest lactose should avoid taking it. Patients with impaired liver function may need to adjust the dosage of this medication, so they must consult their healthcare provider. During the course of this medication, severe side effects such as depression, anxiety, suicidal thoughts, skin rashes, etc., may occur; thus, any abnormal symptoms should be reported to a physician immediately. Consuming alcohol with this medication may further impair mental and motor functions, so alcohol should be avoided. Drug interactions may occur when used in combination with other antiepileptic medications; therefore, inform your healthcare provider of any other medications being taken. The safety for fetal exposure during pregnancy has not been established, so caution should be exercised regarding its use in patients planning to become pregnant or who are pregnant. Women who are breastfeeding should discuss whether to continue breastfeeding as this medication may be secreted in breast milk, with their physician. Safety and efficacy in children under the age of 16 have not yet been fully established, so its use in this age group is not recommended. This medication may cause drowsiness and dizziness, thus caution is advised when driving or operating machinery after taking it. In case of overdose, symptoms may include drowsiness, dizziness, anxiety, and aggression, and as there are no specific antidotes, immediate medical attention should be sought.

• suicidal thoughts
• suicidal behavior
• drowsiness
• fatigue
• dizziness
• coordination impairment
• influenza
• type I hypersensitivity reaction
• neutropenia
• decreased appetite

This medication should be stored in a tightly closed container to prevent air and moisture from entering. It is recommended to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 120 tablets/bottle