Englina Tablet 10/5 mg (Empagliflozin, Linagliptin)

Adult dose

The recommended starting dose of this medication is 10 mg of Empagliflozin and 5 mg of Linagliptin once daily. If there is tolerance to 10 mg of Empagliflozin and 5 mg of Linagliptin and additional blood sugar control is needed, the dose may be increased to 25 mg of Empagliflozin and 5 mg of Linagliptin once daily. This medication can be administered regardless of meals. The tablet should be swallowed whole. If a dose of this medication is missed, take it as soon as remembered.

This medication consists of two active ingredients: Empagliflozin and Linagliptin, primarily used for blood sugar control in patients with type 2 diabetes. This medication should not be administered to patients with allergies to Empagliflozin or Linagliptin, patients with type 1 diabetes, diabetic ketoacidosis, or patients undergoing dialysis. Patients with impaired kidney function should periodically check the efficacy and safety of this medication, especially before and after related medications and kidney function testing. It should be used with caution in patients with mild to moderate heart failure and is not recommended for patients with severe heart failure. Acute pancreatitis may occur while taking this medication; if severe abdominal pain persists, discontinue use immediately and consult a physician. Additionally, if blistering symptoms resembling bullous pemphigoid occur, discontinue this medication and consult a specialist. Urinary tract infections and genital fungal infections may occur frequently, necessitating prompt treatment for any symptoms of infection. There is a risk of hypoglycemia, particularly when taken together with insulin or sulfonylureas; therefore, blood sugar changes should be closely monitored. Symptoms of hypotension or dehydration may occur due to decreased fluid volume, particularly in the elderly or patients on antihypertensive medications, requiring careful monitoring of blood pressure and fluid status. This medication may cause a serious metabolic disturbance known as ketoacidosis; if symptoms such as vomiting, abdominal pain, or breathing difficulties occur, seek medical attention immediately. A rare but serious infection known as perineal necrotizing fasciitis has been reported; if pain or swelling in the perineum occurs, immediate medical attention is required. It is advisable to avoid this medication during pregnancy, and nursing mothers are recommended to discontinue breastfeeding. The safety and efficacy of this medication have not been established in children under 18 years; therefore, it is best not to use in this population. In case of overdose, seek appropriate medical treatment immediately, and this medication should be kept out of reach of children. While taking this medication, caution should be exercised while driving or operating machinery due to the risk of hypoglycemia; immediate action should be taken if symptoms occur.

Serious side effects

Hives, angioedema, ketoacidosis, pancreatitis, bullous pemphigoid, elevated serum creatinine, decreased glomerular filtration rate, pneumonia, pulmonary tuberculosis, sepsis, acute pyelonephritis, acute kidney injury, end-stage renal disease, severe edema with elevated blood pressure, sudden and severe headache, cerebral infarction, intracranial aneurysm, visual disturbances, paralysis, seizures, confusion, asthma attacks, breathing difficulties, chest tightness, cardiac arrest,

Mild side effects

• Urinary tract infections
• vulvovaginitis
• vulvar inflammation
• balanitis
• and other genital infections
• hypoglycemia
• thirst
• cough
• constipation
• oral ulcer formation

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. This will help safely preserve the medication's effectiveness.

Appearance

Yellow film-coated tablets that are convex on both sides and round in shape

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle, PTP - 30 tablets/PTP [10 tablets/PTP × 3]