Empavex 5/1000 mg (empagliflozin, metformin hydrochloride)

Adult dose

The recommended dose of this medication is 1 tablet per dose, taken twice daily. It is determined for each patient considering their therapeutic regimen, efficacy, and tolerability, without exceeding empagliflozin 25 mg and metformin 2000 mg per day. - When used alone with metformin or in combination with other drugs like insulin, the recommended dose is empagliflozin 5 mg taken twice daily (total daily dose of 10 mg) with the existing dose of metformin. - Excellent tolerability.

This medication helps control blood sugar levels. Rare side effects such as severe lactic acidosis may occur during treatment. Caution is needed when used with other diabetes medications, as hypoglycemia may occur. Patients with moderate to severe renal impairment, acute kidney problems, severe infections, or heart failure should not take this medication. It should be temporarily discontinued prior to examinations using iodinated contrast agents and resumed only after normal kidney function is confirmed. It is also advisable to discontinue use for a certain period prior to surgery and to resume post-recovery. Patients who consume alcohol excessively or have impaired liver function should avoid using this medication. Women who are pregnant or breastfeeding should not use this medication. Regular kidney function tests should be conducted while on this medication, and any symptoms of hypoglycemia or infection should be reported to a healthcare provider immediately. This medication may increase the risk of urinary and genital infections, so prompt treatment is necessary if infection symptoms arise. Vitamin B12 levels may decrease; thus, a B12 test is recommended for prolonged use. Gastrointestinal disturbances such as dizziness, vomiting, diarrhea, and abdominal pain may occur, and if symptoms are severe, consultation with a physician is necessary. Elderly patients are at higher risk of renal impairment and should take special care during use. Blood sugar control should be regularly monitored during treatment, and proper measures must be taken in case of hypoglycemic symptoms. In case of overdose, immediate hospital visit for appropriate treatment is required, especially if symptoms of lactic acidosis arise, which need emergency treatment. Keep the medication out of reach of children and store it in its original container.

Serious side effects

• Hives
• angioedema
• severe swelling (edema)
• ketosis
• lactic acidosis
• urosepsis
• pyelonephritis
• perineal necrosis
• stroke
• myocardial infarction

Mild side effects

• Hypoglycemia
• urinary tract infections
• genital infections
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is recommended to maintain a room temperature between 1 degree and 30 degrees Celsius for safe storage of the medication's effectiveness.

Appearance

A yellow, brownish, double-convex, film-coated tablet.

Package unit

60 tablets/bottle, 60 tablets/box [10 tablets/PTP x 6]