Donghwa Memantine Tablet 20mg (Memantine Hydrochloride)

Adult dose

This medication should be taken orally once daily and should be administered at the same time each day. If necessary, it may be taken twice daily. The maximum daily dose is 20mg, and it should be gradually increased by 5mg weekly for the first three weeks to reach the maintenance dose. - First week (Days 1-7): Administer 5mg once daily - Second week (Days 8-14): Administer 10mg once daily - Third week (Days 15-21): Administer 15mg once daily

This medication should not be used in patients with allergies to its components, severe liver dysfunction, or significantly impaired kidney function. It should be administered with caution in patients with epilepsy or those who have a history of seizures, as well as in individuals predisposed to seizures. Additionally, patients taking drugs acting on NMDA receptors such as amantadine, ketamine, or dextromethorphan are at increased risk of side effects, and this medication should not be used together with them. Patients with dietary habits or specific conditions that can increase urinary acidity (pH) should be closely monitored during treatment. Recent cases of myocardial infarction, congestive heart failure, and uncontrolled hypertension require caution, as the safety of this medication has not been fully established in these patient populations. During treatment with this medication, side effects such as dizziness, headaches, constipation, drowsiness, hypertension may occur, and in severe Alzheimer's patients, hallucinations or psychotic symptoms can occasionally appear. This medication can interact with other drugs, so it is important to consult with a physician or pharmacist, especially if taking NMDA antagonists, antipsychotic medications, skeletal muscle relaxants, or anticoagulants. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of taking this medication, and breastfeeding women are advised to discontinue breastfeeding as this medication may be excreted in breast milk. The safety and efficacy of this medication in children or adolescents under 18 years have not been established. In cases of overdose, severe symptoms in the central nervous system and gastrointestinal tract may occur, so strict adherence to the prescribed dosage is necessary, and immediate medical attention should be sought in case of overdose. Finally, this medication may decrease patient responsiveness, increasing the risk of accidents while driving or operating machinery, so caution is required. Lastly, this medication should be stored out of reach of children, and transferring it to another container is not recommended as it aids in maintaining the quality of the medication.

Serious side effects

• Seizures
• hallucinations
• psychotic reactions
• heart failure
• venous thrombosis/thromboembolism
• dyspnea
• pancreatitis
• hepatitis

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• confusion
• hallucinations
• psychotic reactions
• balance disturbances
• gait abnormalities

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The recommended storage temperature is between 1 to 30 degrees Celsius at room temperature. This helps maintain the medication's effectiveness for a longer period.

Appearance

Pink oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP × 3], 30 tablets/bottle, 100 tablets/bottle