Amitapen Injection (Acetaminophen)

Adult administration

For adults weighing over 50kg: Administer 1000mg as acetaminophen, 4 times a day. The dosage interval is at least 4 hours. The maximum daily dosage should not exceed 4 grams. For patients with severe renal impairment (creatinine clearance ≤30ml/min): The dosage interval should be at least 6 hours.

Child administration

For children over 33kg (approximately 11 years old) and adults under 50kg: Administer approximately 15mg/kg (this drug is 1.5ml/kg) as a single dose. The dosage interval is at least 4 hours.

This medication must be used as prescribed with precise dosing; an incorrect dose due to confusion between milligrams and milliliters can lead to serious poisoning or death. It is advisable to use appropriate analgesics as soon as oral medication can be administered. Be sure to check if acetaminophen is present in other medications to avoid overdose. Exceeding the recommended dose can lead to severe liver damage, so patients with liver dysfunction should consult a physician before use. Individuals who consume excessive alcohol should consult a specialist before taking this medication, as failure to do so increases the risk of liver damage. If sudden rashes, blisters, or severe allergic reactions occur, discontinue use immediately and inform healthcare personnel. This medication should not be taken by those who are allergic to it, have peptic ulcers, or have severe liver, kidney, or heart disease. Patients with certain asthma conditions or blood disorders, and those taking specific medications, should carefully consult their physicians before using this drug. Children, the elderly, pregnant women, and nursing mothers should use the minimum dose and monitor for adverse reactions, particularly observing their condition closely. Periodic examinations such as liver function tests or blood tests may be required. This drug should not be mixed with other medications and does not affect driving or machinery operation. Overdose may result in symptoms such as nausea, vomiting, appetite loss, and severe cases may lead to liver failure or coma, requiring immediate medical attention. Certain medications may interact with this drug, so it is essential to inform healthcare professionals if any medications are being taken.

Serious side effects

Urticaria, severe swelling (edema), anaphylactic shock, hypersensitivity, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, toxic epidermal necrolysis, generalized pustular dermatosis, angioedema, anaphylaxis, hypersensitivity requiring discontinuation of treatment, fulminant hepatitis, liver necrosis, liver failure, increased liver enzymes, agranulocytosis, neutropenia, leukopenia, thrombocytopenia, coma, acute renal failure, Lyell syndrome.

Mild side effects

• Fatigue
• low blood pressure
• increased liver transaminase levels
• nervous disorders
• rash
• injection site reactions
• maculopapular rash
• pemphigoid-like reactions
• pustular rash
• thrombocytopenia

Store this medication in a sealed container to prevent exposure to air, preferably at room temperature between 1°C to 30°C. This helps maintain the medication's effectiveness and safety.

Appearance

A clear colorless to pale yellow solution in a plastic container for injection.

Package unit

100mL/pack