Medication info
Diemgollin Tablets 30 Milligrams (Nisergoline)

Diemgollin Tablets 30 Milligrams (Nisergoline)

Prescription medicationTabletOral
Ingredient · strength
Nicergoline›30mg / 1 tablet
Manufacturer / importer
Dasan Pharmaceutical Co., Ltd.
Appearance
Yellow round film-coated tablet
Packaging
Bottle packaging - 30 tablets/bottle, Bottle packaging - 100 tablets/bottle
Approval status
Active

MFDS item code 202400419 · Approved 2024.02.28 · Insurance code 678602110

Summary

Main use
Treatment of dementia syndrome (memory impairment, difficulty concentrating, etc.)
Who takes it
Adults
Adult dose
* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. Reduce the dose in patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL).

Ingredients

Manufacturer
Dasan Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of dementia syndrome (memory impairment, difficulty concentrating, etc.)

  • Reduced motivation
  • Atherosclerotic headache in the elderly
  • Memory impairment
  • Concentration disorder
  • Judgment disorder
  • Lack of initiative
View approved original text

This medication is effective in improving the state of reduced motivation due to chronic cerebral circulation disorders following cerebral infarction. It also helps in treating atherosclerotic headaches seen in the elderly and is used as an adjunct in the treatment of hypertension. The 30 mg dosage is used for the treatment of various symptoms of dementia, such as memory impairment, concentration disorders, decreased judgment, and lack of initiative in patients with primary degenerative vascular dementia and complex dementia. This medication contributes to the improvement of these various neurological symptoms, helping the patients' ability to carry out daily activities.

How to take

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 2 ∼ 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, it may be increased to 60 mg. The dose may be reduced after symptoms improve. Reduce the dose in patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL).

Precautions

This medication should not be used in certain patients. Individuals allergic to this medication or ergot alkaloids should not take this medication. It may be dangerous for patients who have recently had a heart attack or have acute bleeding. Additionally, patients taking sympathomimetic medications, those with very slow heart rates, patients with unresolved intracranial bleeding, and patients with orthostatic regulation disorders should avoid this medication. This medication must be administered cautiously to patients with mild bradycardia or renal dysfunction. Digestive system issues such as loss of appetite, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth may rarely occur when taking this medication. Liver function test values may temporarily increase. Cardiovascular abnormalities such as dizziness, orthostatic hypotension, hypertension, increased blood uric acid levels, and blood pressure decrease may also occur. Additionally, neurological symptoms such as drowsiness, headaches, tinnitus, fatigue, and insomnia have been rarely reported. Rarely, hypersensitivity reactions such as skin rash, hives, itching, facial flushing, and heat sensation may occur. When taken with other antihypertensive medications, blood pressure may drop too low, so blood pressure should be checked frequently. Patients with a history of hyperuricemia or gout should be cautious as this medication may affect uric acid metabolism and excretion. After taking this medication, drowsiness or decreased concentration may occur, so caution should be exercised when driving or operating machinery. This medication is metabolized in the liver, so interactions may occur when taken with other medications affecting liver metabolism. Women who are pregnant or may become pregnant should use this medication only when necessary under medical supervision due to the risk of harm to the fetus. Nursing women should avoid taking this medication as it may be excreted in breast milk or should discontinue breastfeeding. Elderly patients may have reduced bodily functions, so dose adjustment is necessary when taking this medication. Safety in children has not been established, so it is preferable not to use it in children. In cases of overdose, blood pressure may temporarily drop, so blood pressure changes should be carefully monitored and necessary actions should be taken. This medication should be stored out of reach of children and kept sealed in the original container to maintain its quality and prevent misuse.

Side effects

Loss of appetite, diarrhea, constipation, nausea, vomiting, nonspecific upper abdominal pain or cramps, thirst, elevated ALT, elevated AST, dizziness, orthostatic dysregulation, hypertension, increased blood uric acid, hypotension, drowsiness, malaise, headache, tinnitus, fatigue, insomnia, rash, urticaria, itching, flushing, heat sensation, nightmares, mood disturbances, indigestion

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. This will help maintain the medication's effectiveness for longer.

Appearance and packaging

Appearance

Yellow round film-coated tablet

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.