MK Nisergoline Tablet 30 mg

Adult dose

* 5 mg, 10 mg Adults: Administer 5 ∼ 10 mg of nicergoline orally 3 times daily before meals. Adjust the dose as appropriate according to symptoms. * 30 mg Adults: Administer 30 mg of nicergoline orally once daily before a meal. If the desired effect is not achieved at this dose, the dose may be increased to 60 mg. The dose may be reduced after symptoms improve. For patients with impaired renal function (serum creatinine >175 µmol/L) (2 mg/dL), administer a reduced dose.

This medication should not be used in certain patients. People allergic to this medication or ergot alkaloids should not take it. Patients with acute myocardial infarction or acute bleeding may also face risks when using this medication. Patients already taking sympathomimetics, patients with very slow heart rates (less than 50 beats per minute), patients who have not fully hemostatic after intracranial bleeding, and those with orthostatic dysregulation should avoid using this medication. Patients with mild bradycardia or renal function issues should use this medication cautiously. While taking this medication, gastrointestinal problems such as anorexia, diarrhea, constipation, nausea, vomiting, abdominal pain, and dry mouth may rarely occur. There may also be an increase in liver function test results. Circulatory issues such as dizziness, orthostatic hypotension, hypertension, blood pressure reduction, and elevated blood uric acid levels may occur infrequently. Central nervous system symptoms like drowsiness, fatigue, headache, tinnitus, and insomnia have also been reported. Allergic reactions such as skin rashes, hives, itching, flushing, and heat sensations can occur. Taking this medication with other antihypertensive agents may cause excessive hypotension, so blood pressure should be monitored frequently. Patients with a history of hyperuricemia or gout should take this medication with caution. After taking it, one should be careful when driving or operating machinery. This medication is metabolized by a specific enzyme (CYP4502D6) in the liver, which may interact with other drugs that use the same metabolic pathway. Women who are pregnant or may become pregnant should only use this medication when deemed absolutely necessary by a physician, as it could harm the fetus. If breastfeeding, this medication may be excreted in breast milk, so it should be avoided if possible, or breastfeeding should be stopped. Elderly individuals may have reduced body functions, so dosage adjustments may be necessary. Safety for children has not yet been established, so it is advised not to use it in children. In case of overdose, blood pressure may temporarily decrease, so blood pressure changes should be carefully monitored and necessary actions taken. This medication should be stored out of the reach of children and kept tightly closed in its original container. Transferring to other containers may compromise the quality or risk misuse of the medication.

Loss of appetite, diarrhea, constipation, nausea, vomiting, occasional upper abdominal pain or spasms, thirst, elevated ALT, elevated AST, dizziness, orthostatic regulation disorder, hypertension, elevated blood uric acid, hypotension, drowsiness, fatigue, headache, tinnitus, fatigue, insomnia, rash, urticaria, itching, flushing, heat sensation, nightmares, mood disturbances, indigestion

This medication should be stored in a tightly closed container that blocks light, preferably at a temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain its effectiveness and prevents deterioration.

Appearance

Yellow round film-coated tablets

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 60 tablets/bottle