Abilify Tablet 1 mg (Aripiprazole)

Adult dose

For the treatment of schizophrenia, the recommended initial dosage is 10 mg or 15 mg once daily, regardless of food, and may be adjusted within a range of 10-30 mg per day. Maintenance therapy is administered at a dosage of 15 mg per day for at least 3 months. For the treatment of acute mania or mixed episodes associated with bipolar disorder, the recommended initial dosage is 15 mg once daily, regardless of food, with an increase up to 30 mg based on clinical response.

Child dose

The recommended dosage for adolescents (ages 13-17) with schizophrenia is 10 mg once daily, regardless of food. The initial dose starts at 2 mg, increasing to 5 mg after 2 days, then to 10 mg after another 2 days.

This medication may increase the risk of suicidal thoughts and behaviors in children, adolescents, and young adults with depression or other psychiatric disorders, so physicians should carefully assess the need for treatment against the associated risks. Close monitoring of emerging suicidal tendencies or behavioral changes is advised after treatment initiation in all age groups, and family members or guardians should observe the patient closely. This medication is not approved for the treatment of pediatric depression. During treatment, serious side effects known as neuroleptic malignant syndrome may occur; if symptoms such as high fever, muscle rigidity, or altered mental status develop, immediate medical attention should be sought. There may be irreversible movement disorders known as tardive dyskinesia, so the lowest possible dose should be used with regular monitoring of the patient's condition during long-term use. In elderly patients with dementia, the use of this medication may increase the risk of stroke or other vascular accidents and mortality; thus, it is not recommended for the treatment of dementia. Hyperglycemia or worsened diabetes has been reported, so diabetic patients or those at risk should periodically check their blood sugar levels. Due to the risk of venous thromboembolism, risk factors for thrombosis should be evaluated and preventative measures considered before and during the use of this medication. It should not be administered to patients with hypersensitivity or lactose intolerance, and caution is advised when used in patients with orthostatic hypotension, a history of seizures, or cognitive and motor impairments. This medication may cause a range of side effects, including drowsiness, dizziness, insomnia, anxiety, extrapyramidal symptoms, so caution is required when driving or operating machinery. In particular, close observation for side effects and suicidal risk is necessary during initial treatment or dose adjustments, and treatment plans should be re-evaluated in case of severe or sudden symptoms. Care should be taken to ensure that this medication is not used for the treatment of attention-deficit hyperactivity disorder (ADHD).

Serious side effects

Hives, severe swelling (edema), difficulty breathing, chest tightness, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in mucous membranes of the mouth or eyes, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, markedly decreased urine output, systemic swelling with elevated blood pressure, severe allergic reactions.

Mild side effects

• Nausea
• vomiting
• constipation
• headache
• dizziness
• akathisia
• anxiety
• insomnia
• restlessness
• drowsiness

This medication can be sensitive to air and moisture, so it should be stored in a tightly closed container. It is best to keep it at room temperature, avoiding extremes of heat or cold, ideally between 1°C and 30°C.

Appearance

White oval tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 200 tablets/bottle, Bottle - 100 tablets/bottle