Widiane Duo Tablets 12.5/1000 mg

Adult dose

The recommended dosage for this medication is 1 tablet once, twice a day. The maximum recommended daily doses for each ingredient do not exceed empagliflozin 25 mg and metformin 2000 mg. - If sufficient blood sugar control is not achieved with metformin alone or with other drugs such as insulin, patients should take empagliflozin 5 mg twice a day (total 10 mg) along with the existing dose of metformin. - Empagliflozin 1

This medication can cause serious side effects such as severe lactic acidosis; if such symptoms appear, immediate medical attention is required. Also, caution is needed as hypoglycemia may occur when used in combination with insulin or sulfonylurea medications. This medication should not be used in patients with moderate or severe renal impairment or in those with acute renal failure. Use should be stopped or approached with caution during unstable physical conditions such as acute infections, heart failure, or pre- and post-surgery. It is safer for pregnant or breastfeeding women not to take this medication. This medication helps with blood sugar control but may cause side effects such as hypoglycemia, urinary tract infection, genital infection, increased urination, nausea, vomiting, diarrhea, abdominal pain, loss of appetite, constipation, abnormal liver function tests, hepatitis, altered taste, itching, rash, erythema, hives, angioedema, urination difficulties, thirst, increased serum lipids, increased serum creatinine, decreased glomerular filtration rate, decreased fluid volume, headache, dizziness, weakness, chest discomfort, chest pain, fever, edema, fatigue, facial swelling, and insomnia. Additionally, blood vitamin B12 levels may decrease, so it is advisable to have regular blood tests. Alcohol consumption can increase the risk of lactic acidosis, so it should be avoided during treatment. During the use of this medication, kidney function and fluid status should be regularly monitored to ensure there are no abnormalities. If undergoing surgery or tests using iodinated contrast agents, this medication should be stopped for a certain period, and use should only resume after confirming normal kidney function. Elderly patients have a higher risk of renal function decline and fluid loss, so dosage adjustment and regular testing are necessary. In case of overdose, serious side effects like lactic acidosis may occur, so it should be taken exactly as directed by a physician. Finally, keep this medication out of reach of children and store it in its original container to maintain quality.

Serious side effects

• Hives
• angioedema
• chest tightness
• difficulty breathing
• lactic acidosis
• severe allergic reactions
• ketoacidosis
• urinary sepsis
• pyelonephritis
• perineal necrosis

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, ideally at room temperature between 1 and 30 degrees Celsius. Keeping it this way will help maintain the medication's efficacy.

Appearance

Biconvex oval film-coated tablet with a dark brownish-purple color

Package unit

30 tablets/bottle, 60 tablets/bottle, 60 tablets/box [10 tablets/PTP x 6], 10 tablets/box [10 tablets/PTP x 1]