Empagmet 12.5/850mg

Adult dose

The recommended dose of this medication is 1 tablet once, twice daily. The decision should consider each patient's current treatment regimen, efficacy, and tolerability, keeping the maximum recommended daily doses of empagliflozin 25 mg and metformin 2000 mg in mind. Patients who are unable to achieve sufficient blood sugar control with metformin alone or in combination with other medications such as insulin should take empagliflozin 5 mg twice a day (total daily dose 10 mg) along with their usual dose of metformin.

This medication helps control blood sugar. However, it may cause a rare side effect called severe lactic acidosis, and if this symptom occurs, immediate medical attention is necessary. When used in conjunction with other diabetes treatments, severe hypoglycemic symptoms may occasionally occur, requiring caution. Patients with severely reduced kidney function, acute kidney issues, heart failure, or acute myocardial infarction should not use this medication. The use of this medication should be temporarily discontinued before and after tests using radiographic contrast agents, and it should only be resumed after confirming normal kidney function. Patients scheduled for surgery should discontinue this medication 48 hours before surgery and resume only after kidney function has recovered post-surgery. Patients with liver dysfunction or excessive alcohol consumption may have an increased risk of lactic acidosis while on this medication. Women who are pregnant, possibly pregnant, or breastfeeding are advised not to take this medication. During treatment, regular monitoring of kidney function and blood tests should be conducted to check for irregularities. Hypoglycemic symptoms may arise; hence, blood glucose should be closely monitored, especially when taken with insulin or sulfonylurea medications. Urinary tract or genital infections may occur, so if related symptoms arise, immediate consultation with a physician is recommended. Due to the risk of fluid loss, if symptoms of dehydration, diarrhea, or vomiting occur, medical guidance should be sought. If symptoms such as fever, genital pain, swelling, or rash occur during treatment, immediate notification to medical personnel is required, and if severe, medication discontinuation should be considered. This medication is not recommended for children under 18 years of age, and those over 75 years may require dose adjustments and regular testing due to the risk of decreased kidney function. In case of overdose, the risk of lactic acidosis increases; thus, the prescribed dosage should be strictly followed, and if unusual symptoms occur, one should go to the hospital immediately. This medication should be kept out of reach of children and stored in its original container for safety.

Serious side effects

• Hives, severe swelling (angioedema), chest tightness, difficulty breathing, pallor, severe allergic reactions
• Severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions
• Difficulty breathing or shortness of breath, asthma attack, cough with fever accompanied respiratory issues
• Yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice)
• Sudden and severe headache, lightning-like pain

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is best stored at room temperature, between 1 degree and 30 degrees Celsius.

Appearance

Pink-tinged white, bilaterally convex oval film-coated tablets

Package unit

10 tablets/box (10 tablets/PTP x 1), 60 tablets/box (10 tablets/PTP x 6), 60 tablets/bottle