Omnipar Plus One Injection

Adult dosage

The dose and infusion rate should be determined based on the patient's lipid removal capacity, nitrogen and carbohydrate metabolism abilities, and nutritional requirements. The dose and the size of the bag should be determined according to the patient's condition and weight. - Patients with normal nutritional status or mild metabolic stress: Nitrogen 0.10-0.15 g/kg per day (0.6-0.9 g/kg as amino acids) - Patients under moderate to severe metabolic stress, regardless of nutritional imbalance: Nitrogen 0.15-0.25 g/kg per day (0.9-1.6 g/kg as amino acids) In very special cases (e.g., burns or marked anabolic states), the nitrogen content may be higher.

Children's dosage

The use in children is not recommended.

This medication must be used strictly according to a physician's instructions. If allergic reactions such as fever, chills, rash, or difficulty breathing occur during administration, the infusion must be discontinued immediately. This medication may produce precipitation when mixed with certain drugs, therefore should not be administered simultaneously with drugs such as Ceftriaxone, and the injection equipment must be thoroughly cleaned if used for other drugs. Caution is required for premature or low-birth-weight infants, as they may have lower lipid removal capabilities and experience adverse reactions. This medication should not be given to individuals with allergies to fish, eggs, soybeans, peanuts, or patients with severe liver disease, renal failure, or blood coagulation disorders. Patients with conditions that may affect fat metabolism such as renal failure, diabetes, or liver dysfunction should be administered this medication with caution, and their blood sugar, electrolytes, and liver function should be monitored periodically during treatment. When administering this medication, strict aseptic techniques must be observed to prevent infection, and serum triglyceride levels should be checked regularly to prevent fat overload syndrome due to excessive administration. Excessive administration of amino acids or glucose can cause side effects such as nausea, vomiting, and hyperglycemia; therefore, the recommended dosage and infusion rate must be adhered to. The safety of this medication during pregnancy or lactation has not been established, and it should only be used when the therapeutic benefits outweigh the risks. Blood tests should be performed 5 to 6 hours after administration as fatty components can affect test results. In case of excessive administration, reduce or discontinue the infusion rate and seek appropriate emergency care if necessary. This medication should be stored at a temperature between 1°C and 25°C, kept in a sealed container to prevent air or moisture exposure. After mixing, it should be used promptly, and any remaining solution should be discarded.

Serious side effects

• Fever, rash, difficulty breathing → Anaphylactic reaction
• Intraluminal fat accumulation → Severe respiratory distress
• Jaundice, liver dysfunction
• Coma → Severe neurological disorders
• Increased blood pressure → Severe edema or blood pressure abnormalities
• Increased serum triglyceride concentration → Fat overload syndrome
• Urination disorders and renal failure-related adverse reactions.

Mild side effects

• Paralytic ileus
• intestinal obstruction
• air discharge
• abdominal fluid accumulation
• pulmonary congestion
• fever
• increased alanine aminotransferase
• increased amylase
• increased aspartate aminotransferase
• headache

This medication should be stored in a sealed container to prevent the entry of air and moisture. It is important to maintain a storage temperature between 1°C and 25°C.

Appearance

It consists of a transparent colorless plastic inner bag divided into three compartments and an outer package, with an oxygen absorber placed between the compartments. Each compartment contains a transparent colorless to light yellow amino acid solution.

Package unit

986 mL / bag [A solution 500 mL, B solution 298 mL, C solution 188 mL], 1477 mL / bag [A solution 750 mL, B solution 446 mL, C solution 281 mL], 1970 mL / bag [A solution 1000 mL, B solution 595 mL, C solution 375 mL]