Duvimet ER Tablets 0.25/50/500 mg

Adult dose

This medication is generally administered once daily with the evening meal, with the 0.5/100/1000 mg extended-release tablet taken once daily, 1 tablet at a time. Patients taking the 0.25/50/500 mg, 0.25/50/750 mg, or 0.25/50/1000 mg extended-release tablets should take 2 tablets at once once daily. If adequate blood sugar control is not attained with Metformin and Sitagliptin, this medication can be considered.

This medication should not be used in patients with compromised cardiac function, as it may worsen symptoms of heart failure; careful monitoring by a physician is needed. If signs of heart failure appear, consult a doctor immediately and get evaluated through necessary tests. It is also recommended not to initiate this medication in severely symptomatic heart failure patients. This medication may cause fluid retention, leading to edema or heart failure symptoms, thus patients should periodically monitor these symptoms. Allergic reactions may occur, and if symptoms such as rash, hives, or difficulty breathing appear, discontinue use immediately and inform healthcare personnel. There is a risk of serious pancreatic diseases, such as pancreatitis; thus, if symptoms like abdominal pain, nausea, or vomiting occur, seek medical attention promptly. This medication can rarely cause a serious metabolic disorder called lactic acidosis; if symptoms like sudden fatigue, muscle pain, difficulty breathing, or abdominal pain arise, consult your healthcare provider immediately. Patients with renal function impairment should not use this medication and should have regular kidney function tests. Caution is also required in patients with liver dysfunction, and the medication may be discontinued if liver test results are abnormal. During therapy, any weight gain or edema should be reported to a physician, and it is crucial to combine appropriate exercise with a dietary regimen. This medication carries a risk of hypoglycemia, requiring caution when skipping meals or engaging in vigorous exercise, and immediate action is necessary if hypoglycemic symptoms occur. Pregnant women or those planning to become pregnant should consult a physician before use, while premenopausal women should use adequate contraceptive methods during treatment due to the risk of pregnancy. If one's physical condition is poor due to surgery or severe infections, temporary discontinuation of this medication is recommended, and it may be restarted upon recovery as advised by a doctor. This medication may interact with other drugs; thus, if you are taking any other medications, it is essential to inform your physician or pharmacist. Regular testing of blood sugar, liver function, and kidney function should be done during treatment, and any adverse symptoms should be reported to healthcare personnel immediately.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, visual abnormalities, paralysis, urination problems

Mild side effects

• Headache
• dyspepsia
• upper abdominal pain
• constipation
• diarrhea
• itching
• muscle pain
• osteoarthritis
• joint pain
• hematuria

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is advisable to maintain the storage temperature between 1°C and 30°C.

Appearance

Light blue, bilaterally convex, oval-shaped extended-release film-coated tablet

Package unit

Bottle package - 30 tablets/bottle, bottle package - 6 tablets/bottle