Rosuvastatin 2.5 mg (Rosuvastatin Calcium)

Adult dosage

This medication is taken once daily at any time of the day, regardless of meals. The initial dose is 2.5 or 5 mg once daily, with a maintenance dose of 10 mg once daily; most patients are managed on this dosage. The maintenance dose can be adjusted appropriately based on LDL-cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more, with a maximum increase to 20 mg per day.

This medication should not be used in certain patients. For example, it should not be administered to patients who are allergic to any of its components, have severely impaired liver function, have muscle disorders, are taking cyclosporine, or have very poor kidney function. Additionally, it should be avoided in pregnant or breastfeeding women, and women who may become pregnant and are not using appropriate contraception. This medication may have side effects related to muscle pain or muscle damage; therefore, patients with a history of muscle-related disorders, impaired kidney function, hypothyroidism, or those who consume alcohol excessively should use it with caution. Symptoms such as muscle pain, weakness, or cramps should be reported to a doctor immediately, and blood tests may be necessary to check for muscle damage. Liver function tests should be conducted regularly, and if symptoms of liver damage (fatigue, jaundice, loss of appetite, etc.) appear, the use of the medication should be stopped immediately. This medication may interact with other drugs, so it is essential to inform the doctor or pharmacist about any medications being taken. Particularly, the risk of muscle damage may increase when used with fibrate drugs or certain antibiotics, antifungals, and immunosuppressants. In pregnancy or breastfeeding, this medication may pose a risk to the fetus or baby, so it must be avoided. Women planning to become pregnant should use appropriate contraception. In case of overdose, there is no specific antidote, so one should visit a medical facility immediately for appropriate treatment and monitoring of liver function and muscle damage. While taking this medication, caution should be exercised as dizziness may occur when driving or operating machinery.

Serious side effects

Hives, angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances

Mild side effects

• Dyspepsia
• pruritus
• headache
• dizziness
• constipation
• nausea
• abdominal pain
• myalgia
• asthenia
• itching

This medication should be stored in a tightly closed container to protect it from air and moisture. It is also advised to store the medicine at a temperature between 1 degree and 30 degrees Celsius.

Appearance

White round film-coated tablets

Package unit

Domestic use - 30 tablets/bottle, Domestic use - 100 tablets/bottle