JanuaTin Duo Tablet 50/1000 mg

Adult dose

For diabetes therapy, the dosage of this medicine should be determined considering the current therapy, efficacy, and tolerance of the patient within the maximum recommended daily dosages of sitagliptin 100 mg and metformin 2000 mg each. This medicine is generally taken twice a day with food, and the dosage should be gradually increased to reduce gastrointestinal side effects caused by metformin. 1. For patients currently on metformin

This medicine contains sitagliptin and metformin hydrochloride and is used in the treatment of type 2 diabetes. Severe allergic reactions may occur when using this medicine, so if symptoms such as skin rash, hives, or difficulty in breathing appear, discontinue use immediately and consult a physician. Acute pancreatitis may develop, so if abdominal pain, nausea, vomiting, or fever occurs, inform medical staff immediately. Patients with impaired kidney function, acute heart failure, myocardial infarction, serious infections, or dehydration should not take this medicine and should discontinue it for a certain period before and after surgery. It is safer for women who are pregnant or may become pregnant and for breastfeeding mothers to avoid taking this medicine. This medicine can cause hypoglycemia, so blood sugar changes should be closely monitored, especially when taken with other hypoglycemic medications such as insulin or sulfonylureas. Care is needed as the risk of hypoglycemia increases with vigorous exercise, irregular meals, or nutritional imbalance. Patients with liver dysfunction should avoid using this medication, and excessive alcohol intake may increase the risk of lactic acidosis, so it should be avoided. Regular monitoring of kidney function and hematological tests is recommended during treatment with this medicine, and periodic checking of vitamin B12 levels is advisable. There may be interactions with other medications when taken concurrently, so it is essential to inform medical staff if you are taking other medications. If an overdose occurs, seek medical attention immediately for appropriate treatment, and blood dialysis may be necessary. This medicine is not recommended for use in children, especially those under 18 years of age, as safety and efficacy have not been established. Elderly patients should monitor their kidney function closely due to possible decline, requiring dose adjustments and regular function tests. During treatment with this medicine, a diet and regular exercise should be maintained, and immediate consultation with a physician is advised if any abnormal symptoms appear.

Serious side effects

Hives, severe allergic reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome, and exfoliative skin diseases), acute pancreatitis (including hemorrhagic or necrotizing), acute renal failure, difficulty breathing, severe and disabling arthralgia, bullous pemphigoid, lactic acidosis, severe edema, edema associated with increased blood pressure, acute myocardial infarction, severe infections, liver dysfunction (jaundice and elevated liver enzymes), severe hypoglycemia, severe headache,

Mild side effects

• Diarrhea
• upper respiratory infection
• headache
• nausea
• vomiting
• abdominal pain
• nasopharyngitis
• constipation
• myalgia
• limb pain

This medicine should be kept in a tightly closed container to prevent air or moisture ingress, and stored at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the effectiveness of the medicine.

Appearance

Red-brown oval film-coated tablet

Package unit

Bottle - 100 tablets/bottle, Bottle - 30 tablets/bottle