Dapagreen Tablet 5 mg (Dapagliflozin Propanediol Hydrate)

Adult dose

This medication can be taken orally once daily at any time regardless of food intake. The tablet should be swallowed whole. The recommended dose for monotherapy and add-on therapy is 10 mg once daily. For those with no previous experience in diabetes medication treatment, when administered in combination with metformin, the initial recommended dose is either 5 mg once daily or 10 mg once daily. For chronic kidney disease patients, the dose is once daily.

Child dose

The efficacy and safety of dapagliflozin in children under 18 years have not been established. There are no relevant data.

This medication should not be used in patients who have had allergic reactions to its active ingredients or excipients. Additionally, it should not be administered to patients with type 1 diabetes or diabetic ketoacidosis. This medication contains anhydrous lactose, so patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take it. Patients undergoing dialysis should also avoid using this medication. Patients with reduced fluid volume or kidney function issues should use this medication with caution, and blood pressure and kidney function must be carefully monitored before and after administration. In particular, in patients with moderate or more severe kidney impairment, the blood sugar control effect of this medication may be reduced, so consultation with a specialist is advised. During the use of this medication, genital infections or urinary tract infections may occur, so immediate treatment is necessary if symptoms of infection arise. There may be symptoms of hypoglycemia, so when used with insulin or sulfonylureas, dosage adjustment may be required. This medication can cause dehydration or low blood pressure, so if reduced fluid volume is suspected, temporary cessation of use may be necessary. Severe metabolic abnormalities, such as diabetic ketoacidosis, can occur, so if symptoms like vomiting, abdominal pain, or shortness of breath occur, healthcare professionals should be notified immediately. Patients with severely impaired liver function, pregnant women, and breastfeeding women should avoid taking this medication. Elderly patients are at a higher risk of kidney impairment and reduced fluid volume, so extra caution is needed. Also, the safety and efficacy of this medication have not been established in children, so it should not be used in pediatric patients. In case of overdose, seek immediate medical attention, and while this medication does not significantly affect driving or operating machinery, caution is advised considering the risk of hypoglycemia. Finally, this medication should be stored in its original packaging and kept out of reach of children.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucous membranes, shortness of breath or difficulty breathing, asthma attacks, breathing problems accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urine

Mild side effects

Vulvovaginal inflammation, glansitis and related genital infections, urinary tract infections, fungal infections, hypoglycemia, dry mouth, dizziness, constipation, oral dryness, back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, elevated blood creatinine, dyslipidemia, weight loss, rash, angioedema, gastrointestinal disorders (gastroesophageal reflux disease, abdominal pain, diverticulitis, bowel perforation, acute pancreatitis, chronic pancreatitis, chronic gastritis,

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature.

Appearance

Yellow, bilaterally convex, round, film-coated tablet

Package unit

Box - 28 tablets/box [14 tablets/PTP (Alu-Alu) x 2], Bottle - 30 tablets/bottle, Bottle - 300 tablets/bottle