Dapaglime Tablet 10mg (Dapagliflozin Propanediol Hydrate)

Adult dose

The recommended dose of this medication is 10 mg once daily. It can be taken orally at any time of day, regardless of meals. The tablet should be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in pediatric patients under 18 years of age have not been established.

This medication should not be used in certain patients. Patients who are allergic to the active ingredient or any additives, patients with type 1 diabetes or diabetic ketoacidosis, those with lactose intolerance or related genetic disorders, and patients on dialysis should not take this medication. Patients with reduced fluid volume or decreased kidney function should use this medication with caution. This drug may lower blood pressure or affect kidney function, so fluid status and kidney function should be carefully evaluated before administration, and blood pressure symptoms and changes in kidney function should be closely monitored during treatment. Especially in patients with significantly decreased kidney function, the blood sugar control effect of this medication may be reduced, and administration is not recommended. This medication can cause side effects such as genital infections, urinary tract infections, hypoglycemia, decreased fluid volume, and ketoacidosis. Genital infections may occur more frequently in women and those with a past history of infections, so caution is needed. Hypoglycemia may occur more commonly when this medication is used with insulin or sulfonylureas, so blood sugar should be carefully managed in such cases. Due to decreased fluid volume, dehydration or hypotension may occur, so elderly patients or those taking diuretics should monitor their fluid status closely. Ketoacidosis can occur even when blood sugar is within the normal range, so immediate medical attention should be sought if symptoms such as nausea, vomiting, abdominal pain, or difficulty breathing arise. This drug is not recommended for patients with severely impaired liver function, and should be avoided in women who are pregnant or breastfeeding. Additionally, glucose may be detected in urine tests during the use of this medication. When this medication is taken with insulin or sulfonylureas, dosage adjustments of these medications may be necessary to reduce hypoglycemia risk. In case of overdose, there is no specific antidote, and appropriate treatment should be provided according to symptoms; it has not been confirmed whether dialysis can remove this medication. Lastly, the safety and efficacy of this medication have not been established in children, so it should not be used in pediatric patients. During the use of this drug, caution should be exercised for symptoms of hypoglycemia when driving or operating machinery, and medication should be kept out of the reach of children.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in the mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory signs with cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden severe headache, lightning headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination issues

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infections, fungal infections, hypoglycemia, thirst, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, interstitial nephritis, increased hematocrit, decreased renal creatinine clearance at the beginning of treatment, dyslipidemia, increased serum creatinine at the beginning of treatment, elevated blood urea, weight loss, urticaria, cold sweat, dermatitis, dry skin, hyperkeratosis, skin lesions

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. Additionally, it is safe to store the medication at room temperature, which is between 1°C and 30°C, avoiding extremely hot or cold places.

Appearance

Yellow, biconvex, diamond-shaped film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTP×2)]