Posidapa MR Tablets 10/1000 mg

Adult dose

This medication is typically administered once daily with the evening meal. The maximum dose is once daily dapagliflozin 10 mg/extended-release metformin 2000 mg, taking 2 tablets of 5 mg/1000 mg. When used as initial therapy, the recommended starting dose is once daily 1 tablet of 5 mg/500 mg or 10 mg/500 mg. The recommended dose of dapagliflozin for patients already undergoing treatment with metformin is 10 mg once daily.

This medication is for the treatment of diabetes and may very rarely cause a serious side effect known as lactic acidosis, which can be life-threatening. Caution is required as hypoglycemia may occur when used in conjunction with insulin or sulfonylureas. This medication should not be administered to patients with moderate to severe renal impairment, dehydration, severe infection, or conditions that may affect renal function such as acute myocardial infarction. Pregnant or breastfeeding women, patients with certain genetic diseases, and patients undergoing dialysis should also not use this medication. Patients with reduced fluid volume or renal impairment should use this medication cautiously, and renal function and blood pressure should be regularly monitored before and during administration. This medication may cause side effects such as genital infections, urinary tract infections, hypoglycemia, reduced fluid volume, and ketoacidosis in some patients, so any symptoms should be reported to a physician immediately. Additionally, patients with impaired liver function have a higher risk of lactic acidosis and should avoid this medication. If iodine contrast tests are to be performed before or after taking this medication, it should be stopped 48 hours prior and resumed only after confirming normal renal function. Elderly patients or those with impaired renal function should adjust doses carefully and monitor renal function regularly. Excessive alcohol intake can increase the risk of adverse effects of this medication, so it should be avoided during treatment. This medication may cause Vitamin B12 deficiency, so serum B12 levels should be monitored during long-term use. In case of an overdose, medical attention should be sought immediately, and dialysis may be necessary. Dizziness may occur while driving or operating machinery during treatment with this medication, so caution is advised. Finally, this medication should be stored out of reach of children and kept in its original container to prevent quality deterioration.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, chest tightness, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, difficulty breathing or severe asthma attacks, cough accompanied by fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, vision problems, paralysis, urination

Mild side effects

Hypoglycemia, dry mouth, dizziness, constipation, oral dryness, back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, initial reduction in renal creatinine clearance, dyslipidemia, initial increase in serum creatinine, serum urea increase, weight loss, diarrhea, nausea/vomiting, Vitamin B12 reduction/deficiency, abdominal pain, dyspepsia, abdominal discomfort, abdominal pain, gastric ulcer, irritable bowel syndrome

This medication should be stored in a tightly closed container to protect it from air and moisture exposure. It is important to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance

Yellow, double convex, oval extended-release film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle