DapaRome Sustained Release Tablet 10/1000 Milligrams

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dose is 10mg of dapagliflozin/2000mg of sustained-release metformin once daily, taken as 2 tablets of 5mg/1000mg. The recommended starting dose for initial therapy is one tablet of 5mg/500mg or 10mg/500mg once daily. To reduce gastrointestinal side effects of metformin, the dosage should be adjusted gradually.

This medication is to help control blood sugar levels and should not be administered to patients with impaired renal function or specific health conditions. It can rarely cause a serious condition called lactic acidosis, so caution is needed in patients with decreased renal function or conditions such as severe infection, dehydration, or acute myocardial infarction. When taken with insulin or sulfonylureas, the risk of hypoglycemia may increase, so dosage adjustments may be necessary. This medication should not be used during pregnancy or breastfeeding, and its safety in children has not been established. While taking this medication, genital infections or urinary tract infections may occur, so immediate consultation with healthcare providers is required if symptoms appear. Patients with low blood pressure or reduced fluid volume may develop symptoms of hypotension or dehydration, so regular monitoring of blood pressure and renal function before and during treatment is necessary. This medication can lower vitamin B12 levels, so long-term users should monitor for vitamin B12 deficiency. Excessive alcohol consumption may increase the risk of side effects from this medication, so it is advisable to avoid alcohol intake while on this medication. Before and after surgery or tests using iodine contrast agents, this medication should be discontinued for a certain period and resumed only after checking kidney function. In case of overdose, immediate medical attention should be sought, and this medication should be kept out of reach of children.

Serious side effects

Lactic acidosis, acute kidney injury and renal dysfunction, severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor), severe skin reactions (severe rash with fever, blistering, skin peeling, pain in the mouth/eyes), respiratory problems (shortness of breath or difficulty breathing, asthma attacks, cough accompanied by abnormal breathing and fever), liver problems (jaundice of the skin or eyes, systemic lethargy)

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infections, fungal infections, hypoglycemia (when used with sulfonylureas or insulin), dry mouth, dizziness, constipation, back pain, dysuria, polyuria, nocturia, vulvar itching, genital itching, increased hematocrit, reduced initial renal creatinine clearance, dyslipidemia, elevated serum creatinine at the start of treatment, increased blood urea, weight loss

This medication is sensitive to air and moisture, so it should be stored in a tightly closed container. Avoid storing in excessively hot or cold places, ideally at room temperature between 1 to 30 degrees Celsius.

Appearance

Yellow, double-sided convex, oval-shaped sustained-release film-coated tablet

Package unit

PTP - 30 tablets/box [(6 tablets/PTP) × 5]