Polmindapaserbangeong 10/500 mg

Adult dose

This drug is usually administered once daily with the evening meal. The maximum dosage is 10 mg of dapagliflozin/2000 mg of extended-release metformin per day, administered as 2 tablets of 5 mg/1000 mg. For patients without prior experience on diabetes drug treatments, the initial dosage for therapy is one tablet of either 5 mg/500 mg or 10 mg/500 mg once daily. To reduce gastrointestinal side effects of metformin, dosages should be adjusted stepwise.

This drug can very rarely cause a serious condition called lactic acidosis, so it should be taken cautiously following a physician's instructions before use. There is a risk of hypoglycemia when this drug is taken alongside other diabetes medications such as insulin or sulfonylureas, so caution is advised. Patients with severely impaired kidney function or acute conditions that can affect kidney function such as dehydration, severe infection, or acute myocardial infarction should not take this medication. Pregnant or breastfeeding women and those allergic to the components of this medication should also avoid taking it. Patients with decreased fluid volume or impaired kidney function should verify their fluid status and kidney function before taking this medication, and should continuously monitor for symptoms of low blood pressure and kidney function during use. This drug may increase the risk of genital infections and urinary tract infections, so if infection symptoms arise, immediate consultation with a physician is necessary. Vitamin B12 levels may decrease, so regular monitoring of vitamin B12 levels is recommended during prolonged use. Excessive alcohol consumption may increase the risk of side effects of this medication, so alcohol should be avoided while taking it. This drug has a strong effect of lowering blood sugar, so special attention should be given to hypoglycemia symptoms, especially when used with insulin or other hypoglycemic agents, and dosage adjustments may be necessary as needed. Before surgeries or radiocontrast examinations, this drug should be temporarily discontinued for a certain period of time, and it should be resumed only after confirming normal kidney function. Elderly patients may have decreased kidney function, so renal function should be frequently checked and dosages adjusted accordingly. If any abnormal symptoms or side effects occur during use, immediate notification to healthcare personnel is required, and especially if there is pain, swelling, or fever in the perineum, urgent treatment is necessary. This medication should not be used in children as its safety and efficacy have not been established.

Serious side effects

• Lactic acidosis
• severe hypoglycemia
• acute renal failure
• acute kidney injury
• kidney dysfunction
• elevated creatinine levels
• decreased creatinine clearance
• severe allergic reactions
• severe skin reactions
• respiratory problems

Mild side effects

• Vulvovaginitis
• balanitis and related genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• thirst
• dizziness
• constipation
• dry mouth
• lower back pain

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and the storage temperature should be maintained at room temperature between 1 degree and 30 degrees Celsius. By storing it this way, the efficacy of the medication can be preserved for a longer period.

Appearance

Pink, double-sided, convex, oval, extended-release film-coated tablet

Package unit

30 tablets/box [(6 tablets/PTP x 5)]