Dilatrend SR Tablet 32 mg (Carvedilol)

Adult dose

This medicine should be taken orally with food. Do not increase the dose or stop taking it without your doctor's instructions. This is an extended-release formulation; do not break, crush, or chew it. Swallow the tablet whole. For reference, the daily doses of this medicine (extended-release formulation) corresponding to those of conventional carvedilol formulations are as follows. Daily dose of conventional formulation / Daily dose of extended-release formulation Twice daily, 3.125mg per dose / Once daily, 8mg per dose Twice daily, 6.25mg per dose / Once daily, 16mg per dose Twice daily, 12.5mg per dose / Once daily, 32mg per dose Twice daily, 25mg per dose / Once daily, 64mg per dose Twice daily, 50mg per dose / Once daily, 128mg per dose 1. Essential hypertension 1) Adults: Take 16mg once daily for 2 days, then increase the dose to 32mg once daily. The usual dose is 32mg once daily for 2 weeks. If the effect is insufficient, the dose may be increased to 64mg once daily. The maximum daily dose of this medicine is 64mg. 2) Older adults: A dose of 16mg once daily may provide sufficient therapeutic effect. If the effect is insufficient after 2 weeks of treatment, the dose may be increased. Administer with caution while monitoring the patient's condition. 2. Chronic stable angina 1) For the first 2 days, administer carvedilol 32mg once daily, then administer 64mg once daily. 2) The usual dose is 64mg once daily for 2 weeks. If a dose increase is needed (excluding older adults), administer 128mg once daily. 3. Congestive heart failure 1) The usual initial dose is carvedilol 8mg once daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 16mg once daily for 2 weeks, then to 32mg once daily for 2 weeks, and then to 64mg once daily. 2) After taking each dose for at least 2 weeks, increase the dose gradually to the maximum dose tolerated by the patient. 3) The minimum effective dose of this medicine is 16mg once daily. The maximum dose is 64mg once daily for patients weighing 85kg or less, and 128mg once daily for patients weighing 85kg or more. 4. Heart rate control in patients with atrial fibrillation Administer 8mg once daily. If the effect is insufficient after 2 weeks of treatment, administer 16mg once daily. If the effect remains insufficient after 2 weeks of treatment, administer 32mg once daily.

This medication affects the heart and blood pressure, therefore it should not be used in patients with certain heart diseases or conduction disorders. Also, patients with respiratory diseases such as asthma or chronic lung diseases, or those with hypersensitivity history may experience worsening symptoms while taking this medication, so caution is required. Diabetic patients may be affected in blood sugar control, so regular blood glucose monitoring is necessary, and patients with low blood pressure or severe liver or kidney dysfunction should use it cautiously. Women who are pregnant or breastfeeding should not take this medication due to potential risks to the fetus or newborn. During this medication, symptoms such as dizziness, fatigue, headache may occur, and if the heart rate becomes too slow or blood pressure drops excessively, immediate medical attention should be sought. Moreover, this medication may interact with other drugs, so if you are currently taking any medications, you must inform your doctor or pharmacist, and do not stop taking it suddenly; it should be gradually reduced according to the doctor's instructions. Special caution is needed for the elderly or children, as safety and efficacy have not been fully established. Finally, this medication should be kept out of the reach of children, and it is recommended to store it in its original packaging.

Dizziness, headache, fatigue, weakness, hallucination, confusion, depression, sleep disorders, nightmares, psychosis, severe bradycardia, shock, complete heart block, heart failure, cardiac arrest, significant hypotension, loss of consciousness, decreased pulse rate, cold extremities, edema, worsening heart failure, worsening renal function, renal failure, increased airway resistance, nausea, diarrhea, abdominal pain, vomiting, constipation, urticaria, itching, lichenoid-like reactions, allergic rashes, changes in serum aminotransferases, thrombocytopenia, leukopenia, hypoglycemia, masking of hyperthyroidism, bradycardia, hypotension, shortness of breath, hypertension in angina, hepatic dysfunction, jaundice, limb pain, decreased tears, sensory disturbances, visual disturbances, eye irritation, dry mouth, urination disorders, sexual dysfunction, allergic reactions, increased triglycerides, increased blood sugar, dyspepsia, memory disturbances, dizziness, headache, peripheral neuropathy, dyspnea, epistaxis, cough, wet cough, nasopharyngitis, tinea corporis, soft tissue infection, chronic tonsillitis, diverticulitis, onychomycosis, sepsis, upper respiratory tract infection, diarrhea, abdominal discomfort, epigastric pain, constipation, palpitations, chest discomfort, chest pain, fatigue, conjunctival congestion, ligament sprain, joint swelling, pruritus, facial flushing, palpitations, heart failure, cardiac flutter, syncope, blood pressure reduction, increased serum uric acid, increased N-terminal brain natriuretic peptide prohormone, nausea, chest discomfort, cold, dry cough, cough, blood pressure lowering, bradycardia, myocardial weakness, cardiogenic shock, cardiac arrest, dyspnea, bronchospasm, vomiting, consciousness disturbances, generalized seizure, toxic epidermal necrolysis, Stevens-Johnson syndrome

This medication should be stored at room temperature between 1°C and 30°C, in a sealed container to prevent air from entering. This will help maintain the efficacy of the medication for a longer period.

Appearance

Brownish-red rectangular sustained-release tablet

Package unit

30 tablets/bottle, 100 tablets/bottle