Tuamine 3%

Adult dosage

Administer by intravenous drip a maximum dose of 1-1.5 g of total amino acids per day per kg of body weight. An infusion rate of approximately 10 g of total amino acids over 60 minutes is desirable, and the principle is to drip 80-130 drops per minute.

Children's dosage

Dosage and infusion rate should be adjusted for children.

This medication must be used according to the physician's instructions and should not be used arbitrarily. It should not be used in patients with hepatic coma or at risk of it, patients with severe kidney impairment, and patients with metabolic disorders that make nitrogen utilization difficult. Patients with heart failure, pulmonary edema, oliguria, anuria, hypernatremia, hyperkalemia, or a history of myocardial infarction should also avoid using this medication. This medication contains amino acids and electrolytes, which can cause specific metabolic abnormalities or allergic reactions, so patients with hypersensitivity should avoid it. Asthma patients or individuals sensitive to sulfites should be cautious as allergic reactions or asthma attacks may occur due to components included in this medication. When using this medication, side effects such as nausea, vomiting, palpitations, and increased blood pressure may occur, and rapid administration of large volumes poses a risk of acidosis. Additionally, various tests including blood sugar, electrolytes, liver and kidney function should be regularly performed while closely monitoring the condition. Particularly, diabetic patients should check their blood sugar levels frequently, and it is important for the elderly to administer it slowly and adjust the dosage accordingly. Pregnant women should consider the necessity and risk of treatment since the safety of this medication has not been fully established. Children or newborns may have immature liver function, so lower concentrations should be maintained, and serum ammonia levels should be checked frequently. When administering this medication, maintain sterility, do not use if the solution has changed color or become cloudy, and follow proper temperature and storage conditions. Infusing the fluid too rapidly may cause chills or vomiting, so it should be administered slowly, and interactions with other medications should be considered.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reaction
• Severe rash, blisters, exfoliation of skin, pain in oral/ocular mucosa, severe skin reactions
• Shortness of breath or breathing difficulties, asthma attacks, cough with fever and respiratory abnormalities
• Yellowing of skin or eyes (jaundice), extreme lethargy
• Sudden and severe headaches, thunderclap headache, seizures, confusion of consciousness

Mild side effects

• Rash
• nausea
• vomiting
• chest discomfort
• palpitations
• tachycardia
• increased blood pressure
• metabolic acidosis
• hypophosphatemia
• alkalosis

This medication should be stored in a sealed container to prevent contact with air and is safely stored at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain its effectiveness and prevents deterioration.

Appearance

A transparent solution that is colorless or pale yellow, filled in a colorless and transparent polypropylene aqueous injection container.

Package unit

100 milliliters / pack, 250 milliliters / pack