Posiro 5 mg (Dapagliflozin Propanediol Hydrate)

Adult dose

This drug can be taken orally once daily at any time of day, regardless of food intake. The tablet must be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in children under 18 years have not been established. There is no relevant data.

This drug should not be used in patients who are allergic to the active ingredient or excipients. It is also not safe for patients with type 1 diabetes, diabetic ketoacidosis, or those on dialysis. Patients with decreased fluid volume or renal impairment should use this drug with caution, and blood pressure and renal function should be closely monitored before and during treatment. This drug may lower blood pressure and cause decreased body fluid volume, which can lead to symptomatic hypotension or worsening of renal function. In patients with moderate renal impairment, the blood sugar control effect may be reduced, thus it is not recommended for patients with significantly impaired renal function. Taking this drug may lead to various side effects such as genital infections, urinary tract infections, hypoglycemia, decreased body fluid volume, and ketoacidosis, so if any unusual symptoms occur, immediate consultation with a physician is required. Genital infections are more common in women and have a higher chance of recurrence in patients with a history of prior infections. The risk of hypoglycemia is higher when this drug is used with insulin or sulfonylureas, and dosage adjustments may be necessary in such cases. In cases of severe fluid volume reduction, dehydration or hypotensive symptoms may occur, so careful monitoring of the patient's condition and adequate fluid intake are necessary. Diabetic ketoacidosis can occur even when blood sugar levels are not high, so if symptoms such as vomiting, abdominal pain, fatigue, or difficulty breathing occur, immediate medical attention should be sought. This drug has limited experience in use among patients with severe hepatic impairment, so caution is warranted, and elderly patients or those taking diuretics are at higher risk of fluid volume reduction and require more careful monitoring. Furthermore, while taking this drug, glucose may be detected in urine tests, so this should be noted. It is recommended that pregnant or breastfeeding women do not use this drug, and if pregnancy is confirmed, use should be discontinued immediately. There is no specific antidote for overdose, so appropriate treatment based on symptoms is crucial. This drug does not significantly affect driving or operating machinery, but caution should be exercised for the risk of hypoglycemia when used in combination with insulin or sulfonylureas. Finally, it is important to store this drug out of the reach of children and in its original container to maintain product quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, peeling skin, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme tiredness throughout the body, sudden severe headache, thunderclap headache, seizures, consciousness confusion, visual disturbances, paralysis, urination

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infections, fungal infections, hypoglycemia, dry mouth, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, elevated hematocrit, increased serum creatinine, reduced initial renal creatinine clearance, dyslipidemia, weight loss, hives, sweating, itching, dyspepsia, nausea, diarrhea, vomiting, headache, chest pain, fatigue, pain, edema, foreign body sensation

This drug may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is also best to store the drug at room temperature between 1 and 30 degrees Celsius, avoiding excessively hot or cold places.

Appearance

Yellow round film-coated tablet

Package unit

28 tablets/box[(7 tablets/Alu-Alu*4)], 30 tablets/bottle, 28 tablets/bottle