Abilify Tablets 1 mg (Aripiprazole)

Adult dose

1. Schizophrenia - The recommended starting dose is 10 mg or 15 mg once daily, irrespective of meals. The dosage may be adjusted within the range of 10-30 mg per day and should not be increased before 2 weeks have passed. - Maintenance therapy should be carried out for more than 3 months at a dose of 15 mg daily, with regular reevaluation of the patient. 2. Treatment of mania and mixed episodes associated with bipolar disorder - The recommended starting dose is 15 mg once daily.

Child dose

1. Schizophrenia in adolescents (13-17 years) - The recommended dose is 10 mg once daily, starting with 2 mg, then increasing to 5 mg after 2 days, and again to 10 mg after another 2 days. - Subsequent increases should be in 5 mg increments.

This medication may increase the risk of suicidal thoughts and behaviors in pediatric, adolescent, and young adult patients with major depressive disorder or other psychiatric disorders; therefore, the physician should carefully assess the need for treatment and risks. During the initial months of treatment or when adjusting the dosage, the patient's condition must be closely monitored for any signs of suicidal tendencies or worsening depression. Family members or caregivers should also carefully observe changes in the patient's behavior and notify healthcare professionals immediately if any atypical signs are noticed. This medication is not approved for the treatment of pediatric depression, and caution should be exercised in patients suspected of having bipolar disorder. Serious side effects can occur, such as neuroleptic malignant syndrome, which can be fatal, hence immediate treatment is required if symptoms such as high fever, muscle rigidity, or changes in mental state arise. Irreversible tardive dyskinesia may develop, so the lowest dose and shortest duration of treatment should be used for long-term administration; consideration should be given to discontinuing the medication if symptoms arise. In dementia patients, the risk of cerebrovascular accidents, such as stroke, may increase, so usage is not recommended. Regular monitoring of blood glucose is necessary in diabetic patients or those with risk factors, as this medication can affect blood sugar control. There is a risk of venous thromboembolism, so caution is warranted in patients with thrombotic risk factors. Patients with hypersensitivity to this medication or lactose intolerance should not use it. It should be administered cautiously in patients with orthostatic hypotension, history of seizures, or impaired cognitive and motor functions, and caution should be exercised while driving or operating machinery due to symptoms such as drowsiness. The ability to regulate body temperature may be diminished, so care should be taken in hot environments or during strenuous exercise. In elderly patients or those with dementia who have dysphagia, there is a risk of aspiration pneumonia, so the medication should be used carefully. Various adverse reactions may occur during treatment; therefore, symptoms such as nausea, vomiting, headache, dizziness, insomnia, anxiety, drowsiness, weight gain, nasopharyngitis, restlessness, tremors, sedation, blurred vision, hypersalivation, drooling, malaise, decreased appetite, stuttering, hyperactivity, sleep disturbances, palpitations, abnormal movements, numbness, hallucinations, gastrointestinal disturbances, urinary disorders, frequent urination, dry mouth, muscle pain, musculoskeletal stiffness, muscle spasms, and limb pain should be closely monitored. In particular, motor disorders such as akathisia, extrapyramidal symptoms, and tremors may occur; if such symptoms appear, consultation with a healthcare professional is advised. Long-term use may lead to weight gain and changes in the electrocardiogram, so regular testing is necessary. The appropriate dosage and duration of treatment should be determined based on the patient's condition, and the treatment plan should be adjusted by consulting a physician immediately in case of adverse reactions or worsening symptoms.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eyes mucosa, shortness of breath, asthma attack, respiratory distress with cough and fever, yellowing of skin or eyes (jaundice), extreme drowsiness, sudden and very severe headache, thunderclap headache, seizure, confusion, vision changes, paralysis, urine

Mild side effects

• Nausea
• vomiting
• constipation
• headache
• dizziness
• akathisia
• anxiety
• insomnia
• restlessness
• drowsiness

This medication can be sensitive to air and moisture, so it should be stored in a tightly closed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius to ensure the drug's effectiveness is preserved safely.

Appearance

White oblong tablet (imprint A-005, 1)

Package unit

30 tablets/box [(10 tablets/PTP×3)], 100 tablets/bottle, 300 tablets/bottle