Bilguard M Tablets 50/500mg

Adult dose

The dosage should be individualized based on efficacy and tolerability within the range of 100mg Vildagliptin and 2000mg Metformin. This medication is usually administered with food or immediately after meals to reduce gastrointestinal adverse effects from Metformin. 1. In cases where there is no prior experience of diabetes medication therapy and sufficient blood sugar control is not possible with monotherapy: The initial dosage of this medication is 50/500mg taken once daily, and it may be gradually increased to 50/1000mg for two times daily, taking one tablet at a time.

This medication can cause severe lactic acidosis or hypoglycemia, so it should not be used especially in patients with moderate to severe renal impairment or heart failure. The medication should be discontinued in patients undergoing radiologic iodine contrast studies and can only be restarted after confirming normal renal function post-examination. Patients with a history of hypersensitivity to this medication or those with type 1 diabetes or diabetic ketoacidosis should not use it. Patients with severe infections, significant trauma, nutritional deficits, liver dysfunction, severe pulmonary diseases, or excessive alcohol consumption should either temporarily discontinue or use this medication with caution. It is advisable for pregnant or breastfeeding women to avoid using this medication. This medication carries a risk of hypoglycemia, so caution is required in cases of irregular meals, intense exercise, or when used in combination with other blood sugar-lowering agents. Possible adverse reactions during use include headaches, dizziness, nausea, and hypoglycemia, and if there are signs of liver dysfunction or skin reactions, one should consult healthcare professionals immediately. Patients should have regular checks of liver and kidney function, especially the elderly or those with reduced kidney function should be more cautious. Alcohol consumption can increase the risk of lactic acidosis, so it should be avoided during treatment. Caution is also necessary when driving or operating machinery due to possible dizziness or hypoglycemic symptoms. In case of overdose, one should promptly visit a medical facility for appropriate treatment, and while this medication can be removed by hemodialysis, some components may not be. This medication is not recommended for children or adolescents under 18 years of age, and dosage adjustment is necessary for the elderly depending on kidney function. It is important to monitor blood glucose and blood counts regularly during the course of treatment.

Serious side effects

• Hives
• severe swelling (including angioedema)
• hepatic dysfunction including hepatitis
• blistering and exfoliative skin lesions
• severe joint pain
• bullous pemphigoid
• lactic acidosis
• acute pancreatitis

Mild side effects

• Headache
• dizziness
• fatigue
• nausea
• gastroesophageal reflux
• diarrhea
• bloating
• chills
• decreased blood sugar
• tremor

This medication may deteriorate when exposed to air or moisture, so it must be stored in a tightly sealed container. It is recommended to keep it at room temperature, between 1 and 30 degrees Celsius, to maintain its efficacy for a longer duration.

Appearance

Bright yellow oval film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP X3]