Myungmoon Vancomycin Injection 500 mg

Adult dosage

Administer 500 mg (potency) of vancomycin intravenously every 6 hours or 1 g (potency) intravenously every 12 hours. Oral vancomycin hydrochloride is administered at a total daily dose of 500 to 2000 mg, divided into 3 to 4 doses, over a duration of 7 to 10 days. Total daily doses should not exceed 2 g.

Children's dosage

Administer 10 mg (potency) per kg of body weight intravenously every 6 hours. Infants should receive 10 to 15 mg (potency) per kg of body weight intravenously every 12 hours. For infants and newborns, an initial dose of 15 mg per kg of body weight is recommended.

This drug should not be used in patients who have experienced severe allergic reactions or shock due to this drug in the past. Patients with allergies to this drug or peptide antibiotics and aminoglycoside antibiotics should also not receive this medication. Patients with hearing impairment or deafness should be administered this drug cautiously and monitored carefully if necessary. Patients with impaired kidney function may require regular monitoring of blood concentrations and dosage adjustments as this drug may accumulate in the body. Caution is advised for patients with liver dysfunction, as there may be a risk of worsening liver function. Elderly patients, premature infants, newborns, and patients with damage to vestibular or auditory organs also require careful monitoring. This drug can occasionally cause severe allergic reactions, skin rashes, fever, nausea, diarrhea, etc., so any unusual symptoms should be reported to medical staff immediately. In particular, if neurological symptoms such as hearing loss, dizziness, or tinnitus occur, administration should be stopped and a specialist consulted. Liver and kidney functions should be regularly monitored, and appropriate measures should be taken if abnormalities are detected. Rapid infusion of this drug may cause side effects such as hypotension or skin rashes, so it should generally be infused slowly for more than 60 minutes. Women who are pregnant or breastfeeding should carefully consider the implications of administering this drug as it may affect the fetus or newborn, and breastfeeding should be avoided or discontinued if administration is necessary. In children, especially those whose kidneys are not fully developed, careful administration is necessary as blood concentrations may increase. Using this drug in conjunction with other medications that may affect the kidneys or nervous system may increase the risk of side effects, thus consultation with medical staff is necessary. In case of overdose, serious side effects such as acute renal failure or hearing impairment may occur, and immediate emergency treatment is required. This drug should be administered only by intravenous injection; intramuscular injection or injection through other routes may cause tissue damage or necrosis. Furthermore, this drug may have chemical instability when mixed with other drugs, so it must be administered according to medical staff instructions. Long-term use may lead to the development of resistant bacteria, therefore it should be used for the minimum necessary duration, and if symptoms such as diarrhea or abdominal pain occur during treatment, medical staff should be notified immediately.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• severe allergic reaction
• high fever with severe rash
• blistering
• skin peeling

Mild side effects

• Loose stools
• diarrhea
• nausea
• vomiting
• abdominal pain
• decreased red blood cells
• decreased white blood cells
• decreased platelets
• increased eosinophils
• dizziness

This medication should be stored in a sealed container to prevent exposure to air, and it is safe to maintain at room temperature between 1°C and 30°C. Storing it this way helps to maintain the medicinal effects for a longer period.

Appearance

A colorless and transparent vial filled with white to pale yellowish-brown freeze-dried powder injection.

Package unit

10 vials/box [500 mg potency/vial]