Tetraf-P Injection

Adult dosage

Children over 12 years and adults - Administer 0.6-0.9 g/kg (as amino acids; nitrogen 0.10-0.15 g/kg) or 0.9-1.6 g/kg (as nitrogen 0.15-0.25 g/kg) per day - Administer 13-31 mL/kg per day (amino acids 0.6-1.6 g/kg, total calories 14-35 kcal/kg) - The infusion rate must not exceed 2.0 mL/kg per hour -

Children's dosage

Children aged 2-11 years - Dose can be adjusted up to 35 mL/kg per day - Infusion rate must not exceed 2.4 mL/kg per hour - Recommended duration is 12-24 hours, do not exceed 14 hours and 30 minutes

This medication must be used under medical supervision, and administration must be stopped immediately if allergic reactions such as fever, chills, rash, or difficulty breathing occur. When used in conjunction with intravenous calcium-containing preparations, a precipitate may form, so they should not be infused simultaneously using the same infusion device, and the infusion line must be thoroughly cleaned before and after use. This drug may be risky in premature and low-birth-weight infants as its lipid components may not be well eliminated from the body. Patients with allergies to fish, eggs, soybeans, peanuts, or those with severe liver, kidney, or blood disorders, as well as those in acute shock, should not use this medication. Patients with specific conditions such as renal failure, diabetes, or impaired liver function should use this drug cautiously, and blood glucose, electrolyte, liver enzyme levels, etc., should be monitored frequently during administration. Care should be taken not to allow blood lipid levels to rise too high during administration, and dosages should be adjusted or stopped if any abnormal symptoms occur. Side effects such as hyperlipidemia, allergic reactions, nausea, vomiting, headaches may occur, so abnormal symptoms should be closely observed. This drug has not been established for safety in pregnant or breastfeeding women, and must only be used when absolutely necessary under a physician's discretion. Because it can affect blood test results, it is advisable to draw blood 5-6 hours after administration when conducting tests. In case of overdose, slow down the infusion rate or stop it, as there are no specific antidotes, supportive care according to symptoms is necessary. This drug should be stored below 25 degrees Celsius in a sealed container to protect it from air or moisture, and must be used immediately after mixing or within 24 hours if refrigerated.

Serious side effects

Anaphylactic reactions (fever, chills, rash, difficulty breathing), urticaria, skin rash, chest tightness, difficulty breathing, cyanosis, pallor, jaundice, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, marked decrease in urine output, severe generalized edema, increased blood pressure, severe swelling, abnormal urination, hyperlipidemia

Mild side effects

Loss of appetite, nausea, vomiting, increased plasma liver enzyme levels, thrombophlebitis, hypotension, hypertension, slight elevation in body temperature, chills, headache, dizziness, skin rash, urticaria, flushing, heat sensation or cooling sensation, pain (in neck, back, bones, chest, waist), nausea, vomiting, chills, sweating, temperature elevation, hyperglycemia, constipation, diarrhea, indigestion, edema, general weakness, hypoglycemia, frequent urination, phlebitis, extravasation at the infusion site,

This drug must be stored in a sealed container to protect it from air and moisture. Additionally, to maintain the drug's effectiveness, it should be stored in a cool place below 25 degrees Celsius, taking care not to freeze it.

Appearance

It consists of a colorless and transparent intravenous plastic bag divided into three separable pouches, with an oxygen-absorbing agent placed in between. Each inner pouch contains a colorless to slightly yellowish transparent amino acid solution.

Package unit

1477 mL/bag (Solution A 750 mL, Solution B 446 mL, Solution C 281 mL)