Empagliflozin 10 mg Tablet (Empagliflozin)

Adult dose

The recommended dosage of this medication is 10 mg once daily for monotherapy and additional combination therapy with other antihyperglycemic agents such as insulin. If there is excellent tolerance and additional blood sugar control is required, the dosage may be increased to 25 mg once daily. This medication can be taken regardless of meals, and the tablet should be swallowed whole. If a dose is missed, take it as soon as remembered; do not take double the dose in one day.

This medication should not be used in patients with an allergic reaction to the active ingredient or any of its components. Do not administer this medication to patients with type 1 diabetes or diabetic ketoacidosis. This medication is not to be used in patients with severely impaired renal function, that is, those with a glomerular filtration rate of less than 30 mL/min/1.73m² or in those with end-stage renal disease or undergoing dialysis. This medication contains lactose, so it should not be given to patients with genetic conditions such as galactose intolerance, lactose deficiency, or glucose-galactose malabsorption. Caution is needed in patients with somewhat impaired renal function, and it is advisable not to initiate this medication in patients with a glomerular filtration rate of less than 60 mL/min/1.73m². If renal function continues to fall below 60 mL/min/1.73m², dosage adjustment or discontinuation of the medication is necessary. This medication is not expected to be effective in patients with end-stage renal disease or those on dialysis. As this medication can affect kidney function, it is important to regularly monitor renal function before and during administration. In patients with heart failure, especially those with mild to moderate severity (NYHA class I-II), careful administration is required, and it is not recommended in patients of severe severity (NYHA class III-IV). When used in combination with insulin or insulin secretagogues such as sulfonylureas, there may be an increased risk of hypoglycemia, so dosage adjustment may be necessary in these cases. Patients should be aware of hypoglycemic symptoms while taking this medication, especially when used with insulin or insulin secretagogues. This medication may lead to side effects such as genital infections, urinary tract infections, and increased urination, so if any unusual symptoms occur, immediate consultation with medical personnel is necessary. This medication may cause hypotension or dehydration related to decreased fluid volume, thus caution should be exercised particularly in the elderly or those with low blood pressure. In severe cases, metabolic acidosis known as ketoacidosis may occur, so prompt treatment is required if symptoms occur, necessitating quick testing. It is advisable for pregnant women not to take this medication, and treatment should be discontinued upon confirmation of pregnancy. Breastfeeding women are also recommended to stop nursing if they are taking this medication. The safety and efficacy of this medication have not been established in children under 18 years of age, so it is not used in this population. No specific toxic symptoms have been reported in cases of overdose, but appropriate treatment is necessary depending on the clinical condition. This medication should be stored out of reach of children and it is advisable not to transfer it to another container. There is a risk of hypoglycemia when operating machinery or driving, particularly when used with insulin, so caution is advised. Regular monitoring of kidney function and blood sugar levels during treatment with this medication is important. Additionally, foot care should be emphasized, and if symptoms such as pain, redness, or swelling in the perineum occur, medical personnel should be informed immediately.

Serious side effects

• Hives
• angioedema
• ketoacidosis
• rash
• perineal necrosis
• urosepticemia
• pyelonephritis
• severe allergic reactions
• severe skin adverse reactions
• respiratory issues

Mild side effects

• Hypoglycemia
• Vulvovaginitis
• Balinitis
• other genital infections
• increased urination
• urinary tract infections
• fluid volume loss
• increased serum creatinine
• decreased glomerular filtration rate
• diarrhea

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius. Storing it this way can maintain the effectiveness of the medication and prevent degradation.

Appearance

Light yellow, double convex, round film-coated tablet

Package unit

30 tablets/bottle