Jardiance 10 mg Tablet (Empagliflozin)

Adult dose

The recommended dosage of this medication is 10 mg once daily for monotherapy and for additional combination therapy with insulin and other blood glucose-lowering agents. If well tolerated and additional blood sugar control is needed, the dosage can be increased to 25 mg once daily. This medication can be taken without regard to meals and should be swallowed whole. If a dose is missed, take it as soon as remembered, but do not take two doses at once.

This medication should not be used in certain patients. First, individuals allergic to the active ingredient or any component of this medication should avoid taking it. Additionally, it should not be administered to patients with type 1 diabetes or those experiencing diabetic ketoacidosis. Patients with severely impaired renal function, defined as a glomerular filtration rate of less than 30 mL/min/1.73m2 or those with end-stage renal disease or who are undergoing dialysis should also refrain from using this medication. This medication contains lactose, so it should not be given to patients with lactose intolerance or genetic lactose enzyme deficiency. Patients with mildly impaired renal function should use this medication with caution. Patients with a glomerular filtration rate of less than 60 mL/min/1.73m2 should not initiate treatment with this medication and those already receiving it may need dosage adjustment or discontinuation. In cases of end-stage renal disease or undergoing dialysis, this medication is not expected to be effective and should not be used. Regular monitoring of renal function prior to and during treatment is essential. Patients with heart failure classified as mild to moderate by the New York Heart Association (Class I-II) should use it cautiously, whereas it is not recommended for those classified as severe (Class III-IV). Additionally, when taken with insulin or sulfonylureas, which are insulin secretagogues, there is a risk of hypoglycemia, and dosage adjustments of those medications may be necessary. Adverse reactions that may occur while taking this medication include hypoglycemia, genital infections, urinary tract infections, increased urination, and reduced fluid volume. In particular, the risk of hypoglycemia may be heightened when taken concurrently with insulin or sulfonylureas, so caution is advised. Serious side effects reported include ketoacidosis, Fournier's gangrene (perineal necrotizing fasciitis), and acute pyelonephritis; if symptoms occur, it is important to consult a physician immediately. This medication may cause fluid volume loss, necessitating caution in elderly patients or those with hypotension or cardiovascular disease during administration. Pregnant women are advised to avoid taking this medication, and it should be discontinued immediately if pregnancy is confirmed. Nursing mothers are also advised to discontinue breastfeeding while using this medication. It should not be used in pediatric patients under 18 years of age, as safety and efficacy have not been established. No specific toxic symptoms have been reported in cases of overdose, but appropriate treatment should be sought in the event of overdose. Store this medication out of reach of children and do not transfer it to other containers for safety. Caution is advised when driving or operating machinery, especially when taken in conjunction with insulin or sulfonylureas due to the risk of hypoglycemia. Regular monitoring of renal function and observation of unusual symptoms during treatment is important, and if any unusual symptoms occur, medical consultation should be sought immediately.

Serious side effects

Hives, angioedema, ketoacidosis, urosepsis, pyelonephritis, Fournier's gangrene, chest tightness, difficulty breathing, cold sweat, pallor, severe swelling (edema), interstitial nephritis, acute kidney injury, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, significant reduction in urine output, severe swelling accompanied by increased blood pressure, chest pain, angina, Prinzmetal's angina, deep vein thrombosis

Mild side effects

• Hypoglycemia
• vulvovaginal candidiasis
• vulvitis
• glansitis
• other genital infections
• itching
• rash
• increased urination
• urinary difficulty
• thirst

This medication should be stored tightly sealed to prevent exposure to air and moisture. It is best kept at room temperature between 1 degree and 30 degrees.

Appearance

Light yellow, double-convex, round film-coated tablet

Package unit

30 tablets/bottle