Aserafen Injection (Acetaminophen)

Adult administration

Adults weighing 50kg or more should receive acetaminophen at 1000mg (as acetaminophen) for intravenous infusion over 15 minutes, administered four times daily, with a dosing interval of at least 4 hours. The maximum daily dosage should not exceed 4 grams. Patients with severe renal impairment should have a dosing interval of at least 6 hours.

Child administration

Children weighing 33kg (approximately 11 years) and above should receive acetaminophen at 15mg per kg body weight (1.5ml/kg of this medication) administered as an intravenous infusion over 15 minutes, with a dosing interval of at least 4 hours. Daily

This medication presents a risk of overdose due to confusion between milligrams and milliliters at the time of dosing, so the correct dosage must be verified before administration. Once oral medication can be taken, it is recommended to use appropriate analgesics immediately. One must check whether acetaminophen is included in other medications to avoid overdose. Exceeding the recommended dosage can cause serious liver damage, so patients with liver dysfunction or a history of liver disease should exercise particular caution. Individuals who consume large amounts of alcohol daily must consult with healthcare professionals before taking this medication, as the risk of liver damage may increase. If symptoms like skin rash, hives, or severe allergic reactions occur after taking this medication, immediate cessation and notification to healthcare professionals are required. People allergic to acetaminophen or this medicine, those with severe liver, kidney, or heart disease, and individuals with aspirin-induced asthma should not take this medication. Caution should be exercised in patients with liver or kidney dysfunction, peptic ulcers, blood disorders, asthma, elderly patients, pregnant women, and nursing mothers, and consulting a healthcare professional is important. This medication may rarely cause various side effects such as liver dysfunction, blood disorders, neurological issues, and skin rashes; report any unusual symptoms to healthcare professionals immediately. This medication may interact with other drugs, so it is crucial to inform about any medications currently being taken, especially when combining with certain antibiotics, anticonvulsants, or anticoagulants. It does not affect driving or operating machinery, but should not be mixed with other medications. Children and the elderly should use the minimum effective dosage and monitor for adverse reactions closely, especially in cases of high fever. During pregnancy, the potential effects of this medication on the fetus should be carefully considered, and in nursing mothers, although a small amount is secreted in breast milk, there are no reports of adverse reactions. Patients with severely impaired kidney function should extend the dosing intervals, and in cases of overdose, immediate medical attention is required for detoxification treatment. This medication has rapid antipyretic and analgesic effects but must be used according to the recommended dosage for safety.

Serious side effects

Hives, hypersensitivity reactions, shock, agranulocytosis, neutropenia, leukopenia, thrombocytopenia, coma, acute renal failure, Lyell's syndrome, acute generalized exanthematous pustulosis, toxic epidermal necrolysis, Stevens-Johnson syndrome, thrombocytopenia, fulminant hepatitis, hepatic necrosis, hepatic failure, increased liver enzymes, angioedema, anaphylactic shock, anaphylaxis, severe skin reactions (acute generalized exanthematous pustulosis, Stevens-Johnson syndrome,

Mild side effects

• Fatigue
• hypotension
• increased liver transaminases
• neurological disorders
• petechial rash
• injection site reactions
• papular rash
• bullous pemphigoid-like reactions
• pustular rash
• nausea

This medication should be stored at room temperature between 1 and 30 degrees Celsius, and it is important to keep it in a sealed container to prevent air or moisture from entering.

Appearance

A clear, pale yellow transparent liquid filled in a colorless and transparent plastic container for injection.

Package unit

100 milliliters/box