Medication info

Puristol Syrup (Inosiplex)

Prescription medicationSyrupOral
Ingredient · strength
Inosiplex›5000mg / 100mL
Manufacturer / importer
Boryung Biopharma Co., Ltd.
Appearance
A colorless to light brown syrup with a caramel flavor
Packaging
Bottle - 500 milliliters/bottle
Approval status
Active

MFDS item code 202007892 · Notified 2020.11.16 · Insurance code 670502291

Summary

Main use
Treatment of viral infections (herpes simplex, shingles, chickenpox, etc.)
Who takes it
Adults · Children
Adult dose
Adults: Administer 3~4 g per day of inosiplex (60~80 mL of this medicine) orally in divided doses of 500 mg~1g (10~20 mL) every 4~6 hours.
Child dose
Children: Administer 50~100 mg/kg of body weight per day orally in 6 divided doses.

Ingredients

Manufacturer
Boryung Biopharma Co., Ltd.

Efficacy & effects

Treatment of viral infections (herpes simplex, shingles, chickenpox, etc.)

  • Herpes simplex
  • shingles
  • chickenpox
  • measles
  • subacute sclerosing panencephalitis
View approved original text

This medication is used for viral infections such as herpes simplex, shingles, and chickenpox. It is also utilized in the treatment of measles and subacute sclerosing panencephalitis (SSPE) that may occur in patients with low immunity. As a medication that helps prevent or treat these diseases, it plays an important role in the management of viral infections.

How to take

Adult dose

Adults: Administer 3~4 g per day of inosiplex (60~80 mL of this medicine) orally in divided doses of 500 mg~1g (10~20 mL) every 4~6 hours.

Child dose

Children: Administer 50~100 mg/kg of body weight per day orally in 6 divided doses.

Precautions

This medication should not be used by patients who have had allergic reactions to this drug or its ingredients. Patients with gout or hyperuricemia or a past history of such conditions should use this medication with caution as the uric acid levels in the blood may increase, potentially worsening symptoms. Patients with urinary stones or kidney stones should also use this medication with caution, as it may raise uric acid levels and exacerbate stone symptoms. Patients with poor kidney function should exercise caution as this medication may delay uric acid excretion. Patients taking digitalis heart medication should take care as this medication may affect the heart. This medication contains caramel, so those with a caramel allergy must consult their doctor before use. Taking this medication may cause gastrointestinal symptoms such as indigestion, diarrhea, constipation, nausea, vomiting, and stomach pain. There may also occasionally be changes in blood cell counts, with possible increases in red blood cells or decreases in white blood cells, alongside increases in platelets. Liver function tests may show elevated levels, so those with liver health issues should be cautious. Allergic reactions such as rashes may rarely occur. This medication can raise blood uric acid levels, causing hyperuricemia. It may also affect the kidneys and urinary system, potentially causing kidney stones or urinary stones, polyuria, elevated blood BUN levels, and hypercalcemia. Neurological symptoms such as headaches, dizziness, fatigue, drowsiness, and insomnia may also occur, so care should be taken when driving or operating machinery. Joint pain or, rarely, interstitial pneumonia-like respiratory issues have also been reported. During treatment with this medication, regular monitoring of uric acid levels in blood and urine, as well as kidney function tests, is recommended. This medication does not have significant interactions with other drugs; however, it should be avoided when used with cortisone, globulins, cytotoxic agents, and anti-lymphocyte globulin. The safety of this medication during pregnancy has not been established, so pregnant women or those who may become pregnant should consult with their doctor before taking it, and it is especially advised to avoid use during the first three months of pregnancy. If breastfeeding, it is advisable to discontinue nursing as this medication can be passed into breast milk. In the case of overdose, symptoms such as vomiting, headache, discomfort in the upper abdomen, dizziness, and palpitations may occur; however, reducing or stopping the dosage will alleviate symptoms. In cases of overdose, appropriate treatment for symptoms and necessary supportive therapy should be implemented.

Side effects

abdominal discomfort, diarrhea, constipation, gastrointestinal bleeding, nausea, vomiting, stomach pain, increased red blood cells, decreased white blood cells, increased platelets, elevated AST/ALT, elevated γ-GTP, elevated ALP, elevated LDH, rash, hyperuricemia, increased BUN, kidney stones associated with hypercalcemia, polyuria, urinary stones, headache, dizziness, fatigue, malaise, neuroexcitability, drowsiness, insomnia, joint pain, interstitial pneumonia, palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, preferably at room temperature between 1 and 30 degrees Celsius. This way, the drug's effectiveness can be maintained for a longer time.

Appearance and packaging

Appearance

A colorless to light brown syrup with a caramel flavor

Package unit

Bottle - 500 milliliters/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.