Sitagliptin 25 mg Tablet (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. Dosage adjustments are necessary for patients with kidney impairment. - Mild renal impairment: no dose adjustment required - Moderate renal impairment (eGFR 45-60): no dose adjustment required - Moderate renal impairment (eGFR 30-45): administer 50 mg once daily - Severe renal impairment

This medication may cause serious allergic reactions in some patients. If symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and consult a doctor. This medication carries a risk of pancreatitis, which is inflammation of the pancreas. If symptoms such as abdominal pain, nausea, or vomiting occur while taking this medication, seek medical attention immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, or in those who have an allergy to this drug or its components. Patients with impaired renal function may require dosage adjustments, so it should be taken according to a doctor's instructions. This medication may cause side effects such as upper respiratory infections, headaches, dyspepsia, diarrhea, among others. Consult a doctor if symptoms are severe. Especially in combination with insulin or sulfonylureas, hypoglycemia may occur more frequently, so blood glucose levels should be checked regularly, and immediate measures should be taken if hypoglycemic symptoms arise. If severe joint pain or blister-like skin reactions occur, discontinue use immediately and consult medical personnel. Pregnant or breastfeeding women should avoid taking this medication, and safety and efficacy have not been established in children or adolescents under 18 years of age. Elderly patients should have their renal function regularly tested due to the likelihood of decreased renal function, which may require dosage adjustments. In case of overdose, treatment may include the removal of the drug from the gastrointestinal tract, and some may be removed by hemodialysis; thus, it is advisable to inform medical personnel in emergency situations. No significant interactions have been reported when used with other diabetes medications or cardiovascular drugs, but all medications being taken should be disclosed to medical personnel.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions (including anaphylaxis, angioedema, Stevens-Johnson syndrome), severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes

Mild side effects

Nasopharyngitis, upper respiratory infection, headache, diarrhea, abdominal pain, nausea, constipation, vomiting, muscle pain, limb pain, back pain, pruritus, thrombocytopenia, blistering dermatosis, severe and disabling arthralgia, dyspepsia, dizziness, increased blood triglycerides, increased low-density lipoprotein cholesterol, hyperglycemia, weight loss, hypernatremia, erectile dysfunction, hypertension

Store this medication in a tightly closed container to prevent air exposure and keep it at room temperature between 1 to 30 degrees Celsius. Proper storage can help maintain the drug's efficacy over time.

Appearance

Pink, round, biconvex film-coated tablet

Package unit

30 tablets/PVC [10 tablets/PVC X3]