Cartren Tablets (Carvedilol)

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension 1) Adults (1) For the first 2 days, take 12.5 mg of carvedilol orally once daily, then take 25 mg orally once daily. (2) The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. 2) Older adults In some older adults, 12.5 mg once daily may be sufficient to achieve the desired effect. However, the dose may be increased if the effect is insufficient after 2 weeks of treatment. 2. Chronic stable angina 1) For the first 2 days, take 12.5 mg of this medicine orally twice daily, then take 25 mg orally twice daily. 2) The usual dose is 25 mg twice daily for 2 weeks. If a dose increase is needed (excluding older adults), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard treatment regimen (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. 1) The usual initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. 2) Increase the dose gradually after taking each dose level for at least 2 weeks, up to the dose the patient can tolerate. 3) The effective minimum dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing more than 85 kg. 4) To control the rate of absorption, it is recommended to take this medicine with meals in the morning and evening. Taking it with meals slows absorption and may reduce the incidence of orthostatic hypotension.

This medication affects the heart and blood pressure and should not be used in patients with certain diseases or symptoms. Administration to patients with very slow heart rates or heart conduction issues, or those with severe heart failure, may pose risks. Additionally, individuals with bronchospasms, such as asthma or chronic obstructive pulmonary disease, should be cautious as this medication may worsen symptoms. Diabetic patients should use this medication carefully as it can affect blood sugar control, and those with severely impaired liver or kidney function should consult a physician before use. Women who are pregnant or nursing should not take this medication as it may cause side effects in the fetus or newborn. While taking this medication, heart function, blood pressure, heart rate, and other parameters should be monitored regularly, and any abnormal symptoms should be reported to a physician immediately. Sudden discontinuation of this medication may worsen cardiac symptoms, so the dosage should be tapered off gradually under a doctor's guidance. Be aware that dizziness or drowsiness may occur while driving or operating machinery, and combining this medication with alcohol can increase blood pressure-lowering effects. This medication may interact with other drugs, so it is essential to inform your doctor or pharmacist about any other medications you are taking. In case of overdose, severe heart problems or breathing difficulties may arise, necessitating immediate medical attention, as this medication is not removed by blood dialysis. When storing this medication, keep it away from light and moisture, and store it out of reach of children.

Dizziness, headache, fatigue, weakness, hallucination, confusion, depression, sleep disorders, nightmares, psychosis, severe bradycardia, shock, complete heart block, heart failure, cardiac arrest, significant hypotension, loss of consciousness, decreased pulse rate, cold extremities, swelling, hypotension, worsening renal function, renal failure, increased resistance in the respiratory tract, nausea, diarrhea, abdominal pain, vomiting, constipation, hives, itching, lichenoid reactions, hyperhidrosis, allergic rash, thrombocytopenia, leukopenia, hypoglycemia, masking of hyperthyroid function, hyperglycemia, weight gain, increased blood cholesterol, bradycardia, hypotension, shortness of breath, hypertension in angina, liver dysfunction, jaundice, limb pain, decreased tears, sensory disturbances, visual impairments, eye irritation, dry mouth, urinary disorders, sexual dysfunction, allergic reactions, toxic epidermal necrolysis, Stevens-Johnson syndrome, changes in serum aminotransferases, changes in liver function parameters

This medication is sensitive to light and should be stored in a container that blocks light. It is also recommended to store it at room temperature between 1 to 30 degrees Celsius to maintain its efficacy and safety.

Appearance

White round tablets

Package unit

90 tablets/box [(10 tablets/PTPX9)]