Rosuvastatin/Ezetimibe Tablets 10/5 milligrams

Adult dose

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, an initial dose of 10/5 mg once daily is recommended. In patients requiring a greater reduction in LDL cholesterol, the dose may be adjusted, and up to 10/20 mg may be increased daily. After starting treatment or adjusting the dose, blood lipid levels should be checked at intervals of more than 4 weeks to adjust the dose.

This medication can cause muscle disorders such as myopathy or, rarely, serious muscle injury called rhabdomyolysis, so if symptoms such as muscle pain or weakness occur, medical consultation should be sought immediately. In cases with risk factors for muscle injury, such as severe infections, hypotension, major surgery or trauma, metabolic disorders, or uncontrolled seizures, the use of this medication may need to be temporarily or permanently discontinued. Patients with hypersensitivity to this medication or those with active liver disease, muscle disorders, or severe renal impairment should not take this drug. Women who are pregnant or may become pregnant, as well as nursing mothers, should also avoid using this medication. Patients with a high risk of muscle injury, such as alcoholics, patients with poor liver function, elderly individuals, and hypothyroid patients, should use this medication with caution. Furthermore, co-administration of certain specific medications can increase the risk of muscle injury, so any ongoing medications should be reported to a doctor or pharmacist. This medication can burden the liver, and periodic liver function tests should be conducted before and during treatment. If blood tests show elevated levels of the muscle damage marker CPK, the use of this medication may need to be suspended. During treatment with this medication, symptoms such as dizziness, headache, indigestion, muscle pain, edema may occur; if symptoms are severe, consultation with healthcare professionals is advised. This medication contains lactose, so patients with lactose intolerance should be cautious. Dizziness may occur during driving or operating machinery; therefore caution is needed. Extra care is required when administering to children or the elderly, and safety in pediatric patients has not been sufficiently established. In case of overdose, there is no specific antidote, so treatment based on symptoms along with liver and muscle function tests is necessary. This medication must be kept out of the reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, jaundice (yellowing of skin or eyes), severe lethargy, sudden and severe headache, lightning headache, seizure, confusion, visual disturbances, paralysis, urine changes

Mild side effects

Headache, nasopharyngitis, indigestion, elevated ALT, edema, muscle pain, chest discomfort, pruritus, dizziness, elevated blood sugar, increased blood lactate dehydrogenase enzyme, elevated CPK levels, elevated liver enzymes, abnormal liver function tests, dry mouth, acute pyelonephritis, constipation, nausea, abdominal pain, itching, diarrhea, loss of appetite, abdominal bloating, fainting, generalized pain, muscle cramps, gout, erectile dysfunction, fatigue, numbness, abnormal sensations, etc.

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Additionally, the storage temperature should be kept between 1 and 30 degrees Celsius at room temperature, avoiding excessively hot or cold places.

Appearance

Pink rectangular film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP x 3], 30 tablets/bottle, 100 tablets/bottle