Sinil Clarithromycin Tablet 500mg

Adult dosage

○ Adults: The usual dose is 250mg (potency) of clarithromycin twice daily. For severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half: administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer this medicine to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it must be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

○ Children 12 years of age and older: Same as the adult dose. ○ For children under 12 years of age, use clarithromycin dry syrup.

This medication should not be administered to patients who are allergic to certain components. Patients who have had hypersensitivity reactions to macrolide antibiotics should also avoid this medication. Patients with a history of QT prolongation or cardiac arrhythmias should use caution as heart problems may worsen while taking this medication. This drug may not be administered to patients with severely impaired liver or kidney function, or dosage adjustment may be necessary. Pregnant or breastfeeding women are advised not to use this medication. This medication can cause serious side effects if taken with certain drugs, so it is essential to consult a physician or pharmacist if currently taking other medications. If any allergic reactions or serious side effects occur during administration, immediately discontinue use and seek medical assistance. Children or the elderly may have different physical responses, necessitating more careful observation when using this medication. Long-term or excessive use of this medication can lead to the development of resistant bacteria; thus, it should be taken only for the prescribed duration under a doctor's instructions. If gastrointestinal disturbances like diarrhea or abdominal pain worsen during use, consult a healthcare professional immediately. Patients with heart disease are advised to regularly check their heart condition through electrocardiogram tests while taking this medication. Due to possible interactions with other drugs that can alter blood drug concentrations, caution is needed when co-administering. This medication can cause dizziness or confusion when driving or operating machinery, so caution should be observed. In case of overdose, gastrointestinal disturbances or neurological abnormalities may arise, so the prescribed dosage should be strictly followed.

Shock, anaphylactic symptoms, difficulty breathing, convulsions, redness, rash, itching, hives, skin redness, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, poor appetite, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucination, psychosis, depersonalization, tremor, paresthesia, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, increased ALP, elevated total bilirubin, increased serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disorder, hearing loss, paresthesia, arthralgia, myalgia, olfactory disorder, auditory disorder, hypoglycemia, tinnitus, hearing impairment, purpuric rash, acute generalized exanthematous pustulosis, muscle cramping, musculoskeletal stiffness, myopathy, increased serum creatinine, elevated blood urea nitrogen, nephritis, venous thrombophlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, muscular weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated blood alkaline phosphatase, increased serum lactate dehydrogenase, increased INR, prolonged prothrombin time, urinary color abnormality

This medication should be stored in a closed container that blocks light, maintaining a storage temperature of room temperature between 15 to 30 degrees Celsius. Proper storage will help ensure the safe effectiveness of the drug.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle