Oakmectin Tablet 375 mg (Amoxicillin and Clavulanate Potassium (2:1))

Adult dose

For adults and children over 12 years or weighing more than 40 kg, administer 250 mg/125 mg of amoxicillin/clavulanate potassium orally three times a day every 8 hours. In cases of severe or respiratory infections, the dose may be increased to 500 mg/125 mg at a time. For renal impairment, adjust dosage according to creatinine clearance. - Creatinine clearance of 30 mL/min or more: dosage adjustment is

Child dose

For children under 12 years or weighing less than 40 kg, the dosage is adjusted similarly to adults in cases of renal impairment.

This medication is a penicillin class antibiotic and should not be used in patients with known allergies to specific components or previous hypersensitivity reactions to beta-lactam antibiotics. Caution is required for patients with viral infections such as infectious mononucleosis or lymphocytic leukemia, as the risk of rash is high. Patients with a history of liver function issues should use this medication cautiously as liver dysfunction may recur upon administration. In patients with liver or kidney impairment, the medication concentration may increase, raising the risk of side effects, thus requiring dosage adjustment and changes in dosing intervals. Individuals with allergic tendencies or those prone to symptoms like bronchial asthma or skin rashes should take this medication with caution. Patients with severe vomiting or diarrhea may not absorb the medication properly, necessitating caution. During medication, promptly consult a physician if abnormal symptoms such as diarrhea, abdominal pain, rash, or difficulty breathing occur, especially since severe allergic reactions or anaphylactic shock may rarely occur, requiring emergency treatment. This medication can affect the liver and kidneys, thus regular liver and kidney function monitoring is recommended for prolonged use. To prevent antibiotic resistance, it should only be taken for the minimum duration as directed by a physician, and should not be stopped or used long-term indiscriminately. Pregnant or breastfeeding women should consult a physician before using this medication, and especially during the first trimester of pregnancy, it is best to avoid its use. Elderly patients have a higher risk of side effects due to decreased bodily functions, thus requiring careful observation and dosage adjustments. Concomitant use with other medications may cause interactions, thus it is essential to inform healthcare professionals of any currently taken medications. In case of overdose, gastrointestinal symptoms, allergic reactions, or kidney damage can occur, therefore immediate medical attention is required.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, high fever accompanied by severe rashes, blisters, skin peeling, pain in oral/eye mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory difficulties accompanied by cough and fever, jaundice (yellowing of the skin or eyes), severe lethargy, liver abnormalities (jaundice), sudden and severe symptoms

Mild side effects

Diarrhea, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, gastric acid abnormalities, soft stools, dry mouth, acute pancreatitis, candidiasis, antibiotic-associated colitis, bloody stools, itching, erythema multiforme, skin rash, dermatitis, serum sickness-like syndrome, arthralgia, lymphadenopathy, thrombocytopenic purpura, prolonged bleeding time and prothrombin time, mucosal candidiasis, vaginal itching

This medication is sensitive to moisture and air; therefore, it should be stored in a tightly sealed container. Keep it packed in moisture-proof packaging to avoid humidity, and store it in a cool place between 1°C and 25°C.

Appearance

White or almost white oval film-coated tablet

Package unit

100 tablets/PTP[(10 tablets/PTP*10)]