Unirine Tablet 0.2mg (Desmopressin Acetate)

Adult dose

Treatment of nocturia associated with nocturnal polyuria (adults only) : Administer desmopressin acetate 0.1mg orally at bedtime. If the effect is insufficient after one week, increase the dose to 0.2mg. If the effect remains insufficient, the dose may be increased at one-week intervals up to 0.4mg. Discontinue treatment if there is no clinical effect within 4 weeks after the dose has been determined. Treatment initiation with this drug is not recommended in patients aged 65 years or older. If treatment is necessary in an elderly patient, closely monitor serum sodium levels, etc. (Refer to 5. General Precautions under Precautions for Use.)

Child dose

Primary nocturnal enuresis (5 years and older) : Administer 0.2mg of desmopressin acetate orally at bedtime. If the effect is insufficient, the dose may be increased to 0.4mg. Whether to continue treatment should be determined after withholding the drug for at least 1 week following 3 months of treatment.

This medication is primarily used to improve symptoms such as enuresis by regulating fluid excretion. However, while taking this medication, fluid intake should be restricted to when thirst is felt. Excessive fluid intake can lower sodium concentration in the body, potentially leading to coma or severe side effects. Additionally, this medication should be avoided in patients with certain conditions. For example, it should not be used in those with allergies to this drug or its components, severe renal impairment, existing hyponatremia, or genetic conditions like lactose intolerance. Patients with high blood pressure, heart disease, chronic kidney disease, pregnant or potentially pregnant women, children, and the elderly should use this medication with extra caution as they are at a higher risk of experiencing hyponatremia or fluid imbalance. While taking this medication, symptoms such as headache, nausea, weight gain, and seizures may occur, and if any of these symptoms arise, immediate consultation with a physician is necessary. Moreover, this medication may interact with other drugs, so it is essential to inform medical professionals about any other medications currently being taken. Special caution is required when taken together with antidepressants, diuretics, steroids, or non-steroidal anti-inflammatory drugs. Pregnant or breastfeeding women should carefully consider the effects this medication may have on the fetus or newborn when deciding to use it, and it is recommended to discontinue breastfeeding if using this medication. In case of overdose, symptoms such as headache, nausea, seizures, and loss of consciousness may occur; in such cases, immediate medical attention is required. Finally, while this medication does not affect the ability to drive or operate machinery, careful monitoring of physical condition while taking this medication is advised.

• Coma
• seizures
• weight gain
• severe water intoxication
• hyponatremia
• allergic reactions
• emotional disturbances
• headache
• abdominal pain
• nausea

This medication may be sensitive to air and moisture, thus it should be stored in a sealed container. Additionally, to maintain the medication's effectiveness, it is important to store it at room temperature between 1 to 30 degrees Celsius.

Appearance

White round tablet

Package unit

30 tablets per bottle