Cefrocti Tablet (Cefuroxime Axetil)

Adult dose

For optimal absorption, take after meals. Adults and children aged 12 years and older Most infections: Administer 250mg twice daily. Severe lower respiratory tract infections, pneumonia, severe infections, or infections suspected to be caused by less susceptible organisms: Administer 500mg twice daily. Urinary tract infections: Administer 250mg twice daily. Uncomplicated gonorrhea: Administer 1g as a single dose. Lyme disease: Administer 500mg twice daily for 14 days (10~21 days). For the treatment of infections caused by Streptococcus pyogenes (Group A beta-hemolytic), this medication should be administered for 7~10 days. Patients with renal impairment: Cefuroxime is primarily excreted by the kidneys. In patients with significant renal impairment, it is recommended that the cefuroxime dose be reduced as follows to compensate for delayed excretion. Creatinine clearance ≥ 30 mL/min/1.73m2; T1/2 (hours) 1.4 - 2.4: No dosage adjustment required (standard dose: 125mg-500mg twice daily) Creatinine clearance 10 - 29 mL/min/1.73m2; T1/2 (hours) 4.6: Administer the standard single dose every 24 hours Creatinine clearance < 10 mL/min/1.73m2; T1/2 (hours) 16.8: Administer the standard single dose every 48 hours Patients receiving hemodialysis; T1/2 (hours) 2 - 4: Administer an additional standard single dose at the end of each dialysis session

Child dose

Infants and children under 12 years of age, most infections: Administer 125mg twice daily. Otitis media in children aged 2 years and older, and severe infections: Administer 250mg twice daily. Infants and children under 12 years of age, Lyme disease: Administer 250mg twice daily for 14 days (10~21 days). There is insufficient experience with use in infants under 3 months of age. This medication must not be divided and is therefore not suitable for treating patients who cannot swallow tablets, such as young infants and children.

This medication is a cephalosporin antibiotic and should not be administered to patients allergic to this class of drugs. Care should be taken when administering to patients with a history or family history of allergy to penicillin or other beta-lactam antibiotics, or those with allergic dispositions. Patients with severely impaired kidney function, those who cannot take medications orally, elderly patients, or those in poor general condition should be carefully monitored as vitamin K deficiency may occur. When using this medication, rare hypersensitivity reactions such as skin rash, urticaria, or anaphylaxis may occur, and if any unusual symptoms manifest, administration should be discontinued immediately. Gastrointestinal and neurological adverse reactions such as headaches, dizziness, diarrhea, nausea, and abdominal pain may occur; if symptoms are severe, consult healthcare professionals. Long-term use may lead to excessive proliferation of Candida or other non-susceptible organisms, and treatment should be discontinued if such symptoms arise. If severe diarrhea or abdominal pain occurs during or after antibiotic use, consider the possibility of pseudomembranous colitis and visit a medical facility immediately. Women who are pregnant or may become pregnant should carefully evaluate the necessity of administering this medication as it may pose risks, and caution is advised during breastfeeding. Safety has not been established for infants under 3 months of age, and for children, it is recommended to use dry syrup formulations instead of splitting the tablets. Elderly patients may experience adverse reactions more frequently due to diminished physiological function; thus, dose adjustment and monitoring are necessary. This medication may cause dizziness when driving or operating machinery, so caution is warranted. There may be interactions with other medications, especially diuretics, aminoglycoside antibiotics, probenecid, and antacids, which should be reported to healthcare professionals. In case of overdose, seizures may occur, so the prescribed dosage must be adhered to, and if unusual symptoms occur, visit a medical facility immediately. This medication should be stored out of reach of children and kept in its original container. Understanding of adverse reactions and precautions is essential, and it is important to consult healthcare professionals immediately if symptoms arise.

• Candida overgrowth
• eosinophilia
• positive Coombs test
• thrombocytopenia
• leukopenia
• granulocytopenia
• erythropenia
• hemoglobin decrease
• hematocrit decrease
• hemolytic anemia

This medication should be stored in a sealed container to prevent air from entering, ideally at a temperature between 1 and 30 degrees Celsius. This helps maintain the medication's effectiveness and prevent degradation.

Appearance

White oblong film-coated tablet

Package unit

50 tablets/box [10 tablets/PTPX5]