Green Cross Donepezil Tablets 10 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

Administer Donepezil Hydrochloride 5 mg once daily before bedtime. For the first 4 to 6 weeks, administer a 5 mg dose, and after evaluating the clinical response, it may be increased to 10 mg. When increasing to 10 mg daily, monitor for gastrointestinal adverse reactions closely. Women over 85 years old who are underweight should not exceed 5 mg daily.

Child dose

There is no experience with the use in children.

This medication contains Donepezil Hydrochloride Monohydrate as its active ingredient and is used for the treatment of symptoms of Alzheimer's type dementia. This medication should not be used by individuals allergic to Donepezil Hydrochloride or the components of this medication, by women who are pregnant or may become pregnant, or by those who are breastfeeding. Additionally, individuals with hereditary lactose intolerance or galactose intolerance should not take this medication. Individuals with a history of heart disease or heart conduction disorders may experience heart-related issues such as bradycardia or arrhythmia while taking this medication, hence caution is necessary. Those taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should use this medication cautiously due to the potential for gastrointestinal bleeding or worsening of ulcers. Individuals with asthma or obstructive pulmonary disease should also be cautious as bronchoconstriction may worsen with this medication. Patients with extrapyramidal disorders such as Parkinson's disease may also experience an exacerbation of symptoms. This medication contains the dye Yellow No. 5, so individuals allergic to this component must notify before use. Serious side effects such as syncope, bradycardia, heart block, myocardial infarction, gastrointestinal bleeding, liver function abnormalities, cerebrovascular problems, motor function disorders, respiratory distress, acute pancreatitis, and kidney failure may occur, so if any abnormal symptoms arise, consult a physician immediately. Common side effects may include nausea, vomiting, diarrhea, dizziness, insomnia, fatigue, and headache, most of which are temporary, but if symptoms are severe, medical professionals should be informed. This medication is used in the treatment of dementia, so regular assessments of its effectiveness should be performed, and if no effect is observed, discontinuation of treatment is recommended. Patients with heart disease or electrolyte imbalance should have their cardiac condition monitored periodically through electrocardiograms, and this medication may affect the ability to drive or operate machinery, so caution is necessary. Since this medication is metabolized in the liver, patients with liver dysfunction should use it cautiously, and liver function tests may be required. Drug interactions may occur when taken with other medications, especially cardiac medications, antidepressants, antibiotics, or anti-inflammatory drugs; hence consultation with healthcare providers is essential. It is safest for pregnant or breastfeeding women not to take this medication; if necessary, consultation with specialists is required. Safety in pediatrics has not been established, so it is not used in children. In case of overdose, severe symptoms such as nausea, vomiting, bradycardia, and respiratory depression may appear; immediate emergency treatment is warranted, and atropine may be used as an antidote. This medication should be stored out of the reach of children, and transferring it to another container may compromise its quality.

Serious side effects

Hives, severe swelling (including facial swelling), chest tightness, difficulty breathing, symptoms of neuroleptic malignant syndrome appearing with sweating, severe allergic reactions, hepatitis, liver function impairment, jaundice, and other liver-related symptoms, severe swelling accompanied by increased blood pressure and edema, syncope, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, Torsades de Pointes, cardiac arrest, heart block.

Mild side effects

Nausea, vomiting, diarrhea, decreased appetite, headache, fatigue, dizziness, insomnia, drowsiness, sweating, itching, rash, muscle pain, muscle cramps, incontinence, frequent urination, constipation, dehydration, fluctuating blood pressure, changes in blood tests (e.g., increased CPK, AST, ALT, etc.), skin rash, aggressive behavior, tremors, and gait disturbances.

This medication should be stored in an airtight container that is well-ventilated, ideally at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness.

Appearance

Yellow, round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle