Roxiem Tablet (Roxithromycin)

Adult dose

(Tablets) Adults: Administer roxithromycin 150㎎ (potency) orally twice daily, in the morning and evening before meals. For pneumonia, administer 300mg (potency) once daily before breakfast. Adjust the dose as appropriate according to age and symptoms.

Child dose

(Pediatric tablets) (Granules) (Suspension) Children: The mean dose used in clinical trials was 6mg (potency) per kg of body weight per day. Administer 5～8mg (potency) per kg of body weight per day orally in 2 divided doses. The dose according to body weight is as follows. Children weighing 6～11Kg: Take 25mg (potency) per dose twice daily before meals (pediatric tablets and granules only); or take 2.5mL per dose twice daily before meals (suspension only). Children weighing 12～23Kg: Take 50mg (potency) per dose twice daily before meals (pediatric tablets and granules only); or take 5mL per dose twice daily before meals (suspension only). Children weighing 24～40Kg: Take 100mg (potency) per dose twice daily before meals (pediatric tablets and granules only); or take 10mL per dose twice daily before meals (suspension only).

This medicine may cause severe blistering skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized exanthematous pustulosis, so if symptoms like blisters on the skin or mucosal damage appear, the use of this medicine should be stopped immediately. Patients with allergies to this medicine or similar antibiotics, or those taking certain medications (terfenadine, astemizole, cisapride, pimodisine, ergot alkaloids, mizolastine) should not use this medicine. Patients with poor liver function or elderly patients, and those using certain antibiotics together face risks of side effects, so caution is advised. This medicine can affect heart electrical signals, so it should be administered cautiously to patients at risk of arrhythmias or those taking certain heart medications. Patients with myasthenia gravis may experience worsening symptoms with this medicine, so it should be used with caution. During use, if sudden allergic reactions, rashes, fever, blood abnormalities, liver function abnormalities, digestive issues (nausea, vomiting, diarrhea, abdominal pain, etc.), respiratory issues (coughing, difficulty breathing), neurological symptoms (dizziness, drowsiness), sensory abnormalities, hearing or vision impairment occur, consult a doctor immediately. In particular, if severe diarrhea or abdominal pain occurs, it may indicate a serious intestinal disease such as pseudomembranous colitis, so use should be stopped immediately and medical personnel informed. Long-term use may lead to the risk of resistant bacteria and secondary infections, so monitoring is essential, and patients with liver dysfunction should undergo regular liver function tests while adjusting the dosage. This medicine may interfere with the metabolism of other drugs in the liver, potentially increasing blood concentrations of certain medications, so it's crucial to inform the doctor or pharmacist when taking with other drugs. Pregnant women or those who may become pregnant should use this medication with caution, and nursing mothers should either stop breastfeeding or avoid using this medicine. Elderly patients do not require dosage adjustments, but they may experience dizziness or visual disturbances; caution is advised when driving or operating machinery. Lastly, this medicine should be stored out of the reach of children, and transferring medications to other containers can compromise their quality, so care is required.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, shock, anaphylactic shock, fever, rash, allergic skin reactions, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, elevated AST, elevated ALT, elevated ALP, increased serum bilirubin, anorexia, nausea, vomiting, upper abdominal discomfort, abdominal pain, abdominal cramping, diarrhea, membranous colitis, loose stools, hemorrhagic colitis, bloody stools, pancreatitis, bronchospasm, cough, shortness of breath, abnormal chest X-ray, interstitial pneumonia, drowsiness, headache, dizziness, tongue numbness, paralysis, dysgeusia, ageusia, olfactory disturbances, anosmia, erythema multiforme, purpura, superinfection due to overgrowth of non-susceptible pathogens, transient hearing loss, auditory impairment, vision disturbances, blurred vision, conjunctival congestion, generalized malaise, fatigue, palpitations, QT prolongation, ventricular tachycardia, arthralgia, epistaxis, menstrual irregularities, inflammation of oral and vaginal mucosa, hallucinations, confusion

This medicine should be stored in a tightly closed container to prevent air or moisture from entering and should be kept at room temperature, ideally between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's efficacy and ensures safe use.

Appearance

White round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle