Ceftriaxone Sodium Injection 1 Gram

Adult administration

Adults and children over 12 years of age should receive 1-2 g (potency) of ceftriaxone once daily via intravenous or intramuscular injection. In cases of severe illness or infections caused by moderately susceptible pathogens, the dose may be increased up to 4 g (potency) once daily. For treatment of gonorrhea, a single intramuscular injection of 250 mg (potency) is recommended. To prevent infections before and after surgery, an administration of 1-2 g (potency) is recommended as a single dose 30-90 minutes prior to the procedure.

Child administration

For newborns (within 14 days of birth), administer 20-50 mg (potency) per kg of body weight once daily, not exceeding 50 mg (potency). For infants and children (from 15 days to 12 years), administer 20-

This medication should not be mixed or administered simultaneously with calcium-containing solutions. In particular, it must not be used with calcium in newborns, as precipitates can form, risking serious side effects. Patients with hypersensitivity to this medication or allergies to cephalosporins and penicillins should not use it. Furthermore, it should not be given to premature infants or newborns with issues related to bilirubin binding, as it may cause bilirubin encephalopathy. Patients with a history of drug allergies, bronchial asthma, or urticaria should use this medicine with caution, and those with impaired kidney function may need dose adjustments. Additionally, patients at risk for vitamin K deficiency should have their coagulation status monitored regularly and supplement with vitamin K as necessary. During administration of this drug, various side effects such as rash, diarrhea, headache, dizziness, blood abnormalities, and liver function abnormalities may occur, so any unusual symptoms should be reported to a healthcare professional immediately. Although rare, severe allergic reactions or shock can occur, requiring careful observation. If diarrhea occurs during antibiotic treatment, consider Clostridium difficile infection and appropriate treatment is required. Additionally, patients with severe renal impairment or the elderly may experience neurological adverse reactions and should be administered with caution. This medication may interact with other antibiotics or diuretics, so it is important to inform the healthcare provider of all medications being taken. Pregnant or breastfeeding women should consult their physician before administration. Injection may cause pain or inflammation at the injection site, so care must be taken regarding the injection method and speed, and prepared solutions should be used as soon as possible. Be cautious of potential dizziness while driving or operating machinery.

Serious side effects

Urticaria, severe swelling (edema), shock, anaphylaxis and anaphylactoid reactions, severe allergic reactions, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, kernicterus due to elevated bilirubin, serious neurological symptoms (encephalopathy, seizures, generalized muscle tremors, non-convulsive status epilepticus), acute renal failure, severe skin adverse reactions, severe hypersensitivity reactions, severe hemolytic anemia, agranulocytosis.

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• elevated liver enzymes
• headache
• dizziness
• bronchial spasm
• loose stools

This medicine should be stored in a sealed container to prevent exposure to air, and it is best kept at a temperature between 1 degree and 30 degrees Celsius.

Appearance

A vial containing a white to pale yellow powder.

Package unit

1 gram X 1 vial, 1 gram X 10 vials