Roxidine Tablets (Roxithromycin)

Adult dose

Adults: Take 150㎎ (potency) of roxithromycin orally twice daily, in the morning and evening before meals. For pneumonia, administer 300mg (potency) once daily before breakfast. Adjust the dose appropriately according to age and symptoms.

Child dose

Children: The mean dose used in clinical trials was 6mg (potency) per Kg of body weight daily. This medicine is administered orally in 2 divided doses of 5～8mg (potency) per Kg of body weight per day. The doses according to body weight are as follows. Children weighing 6～11Kg: Take 25mg (potency) per dose twice daily before meals (for pediatric tablets and granules only), or 2.5mL per dose twice daily before meals (for suspension only). Children weighing 12～23Kg: Take 50mg (potency) per dose twice daily before meals (for pediatric tablets and granules only), or 5mL per dose twice daily before meals (for suspension only). Children weighing 24～40Kg: Take 100mg (potency) per dose twice daily before meals (for pediatric tablets and granules only), or 10mL per dose twice daily before meals (for suspension only).

This medication can rarely cause severe skin reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and acute generalized exanthematous pustulosis. If there are symptoms such as blistering of the skin or progressive skin rash with mucosal damage, discontinue the medication immediately. This medication should not be used by individuals who are allergic to this medication or to macrolide antibiotics, those taking certain heart-related medications, and those on ergots or mizolastine. Caution is required in patients with impaired liver function, elderly patients, and those taking this medication with specific antibiotics. In particular, caution should be exercised in patients with congenital heart rhythm abnormalities or those taking certain antiarrhythmic medications, as this medication may affect heart rhythms. Severe allergic reactions such as anaphylaxis can rarely occur, so if any unusual symptoms occur during the use of the medication, it should be stopped immediately and medical consultation sought. This medication may affect the liver and digestive system; if hepatitis symptoms or abdominal pain and diarrhea occur, discontinue use and inform your physician immediately. This medication may cause hearing loss or dizziness in some patients, and visual disturbances have also been reported. Care should be taken when driving or operating machinery. Additionally, this medication is highly likely to interact with other medications, so inform healthcare professionals of any other medications being taken. Women who are pregnant or breastfeeding should carefully consider the effects of this medication on the fetus or baby when using it, and it is recommended to either avoid use while breastfeeding or stop breastfeeding. For children, the prescribed doses and durations must be strictly adhered to, and overdosing should be avoided. Lastly, this medication should be stored out of reach of children and not transferred to other containers for safety.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, shock, anaphylactic shock, fever, rash, allergic skin reactions, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, increased AST, increased ALT, increased ALP, elevated serum bilirubin, loss of appetite, nausea, vomiting, discomfort in the upper abdomen, abdominal pain, abdominal distension, diarrhea, membranous colitis, loose stools, hemorrhagic colitis, bloody stool, pancreatitis, bronchospasm, cough, dyspnea, abnormal chest X-ray, interstitial pneumonia, drowsiness, headache, dizziness, tongue numbness, paralysis, dysgeusia, ageusia, olfactory disturbances, anosmia, erythema multiforme, purpura, superinfection due to overgrowth of non-susceptible pathogens, transient hearing loss, hearing impairment, visual disturbances, blurred vision, conjunctival injection, generalized malaise, weakness, palpitations, QT prolongation, ventricular tachycardia, arthralgia, nasal hemorrhage, menstrual irregularities, oral and vaginal mucosal inflammation, hallucinations, confusion

This medication must be stored in a tightly closed container to prevent exposure to air or humidity and should be kept at room temperature between 1 degree and 30 degrees Celsius. Avoid direct sunlight and do not store in excessively hot or cold places.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle