Famoton 20mg (Famotidine)

Adult dosage

Oral: 20 mg once, 2 times a day (after breakfast, after dinner or at bedtime) or 40 mg once a day (at bedtime). Alternatively, 10 mg once, 2 times a day (after breakfast, after dinner or at bedtime) or 20 mg once a day (at bedtime). Injectable: Dissolve 20 mg in 20 mL of normal saline or glucose solution and slowly administer intravenously 2 times a day.

This medication should not be used in patients who have previously had an allergy to any of its components or other H2 receptor antagonists. Additionally, it should not be administered to patients with genetic lactose intolerance as it contains lactose. Caution is advised when administering to patients with a history of allergic reactions to medication, poor kidney function, heart disease, impaired liver function, and the elderly. In cases of impaired kidney function, the dose should be reduced or the administration interval extended. Patients with heart disease need to be aware of possible cardiovascular side effects. Observation is necessary for patients with poor liver function as symptoms may worsen. The elderly should use caution as they are at increased risk of decreased kidney function which may raise drug concentration. Rarely, serious allergic reactions, blood disorders, skin diseases, liver dysfunction, muscle damage, cardiac rhythm abnormalities, consciousness disorders, nephritis, pneumonia, and other side effects can occur. Should such symptoms appear, stop using the medication immediately and seek medical attention. Other uncommon side effects may include skin rashes, decreased blood cell counts, gastrointestinal symptoms, blood pressure changes, respiratory spasms, liver function abnormalities, neurological or psychiatric symptoms, and endocrine disorders. It is important to consult a physician if these symptoms occur. During treatment, symptoms, blood tests, and liver and kidney function tests should be monitored regularly, and if no effect is observed, it is advisable to switch to another treatment. The medication dissolves in the mouth but is not absorbed through the oral mucosa, so it must be swallowed with water. If a patient undergoing hemodialysis uses this medication in conjunction with phosphate binders, the effectiveness of some drugs may decrease. Caution is also warranted when combining this drug with certain antifungals or some chemotherapeutics as drug concentrations may decrease leading to reduced effectiveness. Women who are pregnant or may become pregnant should use this medication only when the benefits outweigh the risks, and nursing mothers are advised to discontinue breastfeeding as the drug can be transmitted through breast milk. Safety has not been adequately established in children, and its use is not recommended. Finally, this medication may mask the symptoms of gastric cancer, and should be used only after gastric cancer has been ruled out.

Serious side effects

Shock, hypersensitivity (anaphylaxis, respiratory distress, generalized flushing, angioedema, urticaria), Stevens-Johnson syndrome, Lyell syndrome, liver dysfunction, jaundice, rhabdomyolysis, QT prolongation, ventricular tachycardia, ventricular fibrillation, altered consciousness, seizures, interstitial nephritis, acute renal failure, interstitial pneumonia, failure contraction

Mild side effects

• Rash
• erythema
• urticaria (redness)
• facial swelling
• leukopenia
• eosinophilia
• constipation
• diarrhea
• soft stool
• dry mouth

This medication should be stored in a tightly sealed container to prevent air ingress, and it is safest to keep it at room temperature between 1 degree and 30 degrees Celsius. Proper storage will maintain the medication's efficacy and prevent degradation.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 1000 tablets/bottle