Medication info

Boryeong Carvedilol Tablets 12.5 mg

Prescription medicationTabletOralExpired
Ingredient · strength
Carvedilol›12.5mg / 1 tablet
Manufacturer / importer
Boryeong Co., Ltd.
Appearance
Brownish-red round tablet
Packaging
For domestic use - 90 tablets/box [(10 tablets/PTP x 9)]
Approval status
Expired

MFDS item code 202001745 · Approved 2020.03.13

This product's status changed to Expired on 2025.03.13. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of essential hypertension and chronic stable angina; adjunctive treatment of congestive heart failure
Who takes it
Adults
Adult dose
Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension Adults For the first 2 days, take 12.5 mg of carvedilol orally once daily, then take 25 mg orally once daily. The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. Elderly patients In some elderly patients, 12.5 mg once daily may provide an adequate effect. However, the dose may be increased if the effect is inadequate after 2 weeks of treatment. 2. Chronic stable angina For the first 2 days, take 12.5 mg of this medicine orally twice daily, then take 25 mg orally twice daily. The usual dose is 25 mg twice daily for 2 weeks. If an increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard therapy (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. The usual initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. After taking each dose for at least 2 weeks, increase the dose gradually to the highest dose tolerated by the patient. The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing over 85 kg. To regulate the rate of absorption, it is recommended that this medicine be taken with meals in the morning and evening. Taking it with meals slows absorption and may reduce the incidence of orthostatic hypotension.

Ingredients

Manufacturer
Boryeong Co., Ltd.

Efficacy & effects

Treatment of essential hypertension and chronic stable angina; adjunctive treatment of congestive heart failure

  • Essential hypertension
  • chronic stable angina
  • congestive heart failure
View approved original text

This medication is used to treat essential hypertension, chronic stable angina, and congestive heart failure. It helps to improve symptoms when used as an adjunct with diuretics, digitalis preparations, ACE inhibitors, and other vasodilators. Patients can expect positive effects on blood pressure control and improvement of heart function through this medication.

How to take

Adult dose

Do not increase the dose or stop taking this medicine without your doctor's instructions. 1. Essential hypertension Adults For the first 2 days, take 12.5 mg of carvedilol orally once daily, then take 25 mg orally once daily. The usual dose is 25 mg orally once daily for 2 weeks. If a dose increase is needed, increase to 25 mg twice daily. The maximum dose per administration is 25 mg, and the maximum daily dose is 50 mg. Elderly patients In some elderly patients, 12.5 mg once daily may provide an adequate effect. However, the dose may be increased if the effect is inadequate after 2 weeks of treatment. 2. Chronic stable angina For the first 2 days, take 12.5 mg of this medicine orally twice daily, then take 25 mg orally twice daily. The usual dose is 25 mg twice daily for 2 weeks. If an increase is needed (excluding elderly patients), the dose may be increased to 50 mg twice daily. 3. Congestive heart failure Before starting treatment with this medicine, the patient's existing standard therapy (conventional treatment for chronic heart failure with an ACE inhibitor, a diuretic, and usually a digitalis preparation) must be stable. Fluid retention should also be minimized before starting treatment with this medicine. The usual initial dose is 3.125 mg of this medicine orally twice daily for 2 weeks. If the patient tolerates this treatment well, increase the dose to 6.25 mg twice daily for 2 weeks, then to 12.5 mg twice daily for 2 weeks, and then to 25 mg twice daily. After taking each dose for at least 2 weeks, increase the dose gradually to the highest dose tolerated by the patient. The minimum effective dose is 6.25 mg twice daily. The maximum dose is 25 mg twice daily for patients weighing 85 kg or less, and 50 mg twice daily for patients weighing over 85 kg. To regulate the rate of absorption, it is recommended that this medicine be taken with meals in the morning and evening. Taking it with meals slows absorption and may reduce the incidence of orthostatic hypotension.

Precautions

This medication should not be used in patients with certain health conditions. For example, individuals allergic to this drug or its components, those with severely compromised heart function, and individuals with asthma or chronic lung disease may experience exacerbated symptoms upon taking this medication. Additionally, it is safer for pregnant or lactating women to avoid this medication. Special caution is required for diabetic patients or those with significantly low blood pressure, as well as patients with severe liver or kidney dysfunction. This medication can also pose risks to individuals with bradycardia or conduction issues. Symptoms such as dizziness, fatigue, and headaches may occur during use, and in severe cases, heart function may deteriorate or blood pressure may drop significantly. Abrupt discontinuation of this medication may worsen symptoms of heart disease, so dosages should be gradually reduced under a doctor’s guidance. Interactions may occur when taken with other medications, so it is essential to inform your doctor or pharmacist if you are currently taking other medications. Special monitoring is necessary, particularly when using in conjunction with antihypertensive agents, diabetes medications, and heart medications. This medication may discolor when exposed to light, so it should be stored in a tight container away from direct sunlight, out of reach of children.

Side effects

  • Dizziness
  • headache
  • fatigue
  • weakness
  • hallucination
  • confusion
  • depression
  • sleep disorders
  • nightmares
  • mental illness
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  • severe bradycardia
  • shock
  • complete heart block
  • heart failure
  • cardiac arrest
  • hypotension
  • loss of consciousness
  • decreased heart rate
  • cold extremities
  • edema
  • cardiac arrest
  • worsening renal function
  • renal failure
  • increased respiratory resistance
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • constipation
  • urticaria
  • itching
  • lichenoid-like reactions
  • sweating
  • allergic rash
  • serum aminotransferase changes
  • thrombocytopenia
  • leukopenia
  • hypoglycemia
  • masking of hyperthyroidism
  • hyperglycemia
  • weight gain
  • increased blood cholesterol
  • bradycardia
  • hypotension
  • shortness of breath
  • hypertension with angina
  • hepatic dysfunction
  • jaundice
  • limb pain
  • decreased tears
  • sensory disturbances
  • visual impairment
  • eye irritation
  • dry mouth
  • urinary disorders
  • sexual dysfunction
  • allergic reactions
  • toxic epidermal necrolysis
  • Stevens-Johnson syndrome
  • blood pressure drop
  • decreased heart rate
  • myocardial weakness
  • cardiac arrest
  • cardiogenic shock
  • dyspnea
  • bronchospasm
  • vomiting
  • altered consciousness
  • generalized seizures

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that does not allow light in. It is also important to avoid extremely hot or cold places and store it at room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Brownish-red round tablet

Package unit

For domestic use - 90 tablets/box [(10 tablets/PTP x 9)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.